Enzymatic and Chemoenzymatic Synthes is of Nucleotide Sugars

Synthesis of Nitrogen-Containing Furanose Sugar Nucleotides for Use as Enzymatic Probes

“…It is well established that the enzymatic synthesis of sugar nucleotides can, in many cases, give better yields, selectivity, and shorter reaction times as compared to chemical syntheses. ,, For example, the highest yielding chemical synthesis of UDP-galactofuranose (UDP-Gal f , 10 , Scheme ) gives the desired product in 35% yield, whereas the enzymatic synthesis of this compound carried out by Errey et al produces UDP-Gal f in 79% yield …”