Environmentally friendly method for poly(3-hydroxybutyrate) recovery based on physical adsorption on a solid inorganic inert adsorbent

Macagnan, Karine Laste; Alves, Mariane Igansi; Kesserlingh, Sônia Maria; Vendruscolo, Claire Tondo; Moreira, Angelita da Silveira

doi:10.1016/j.seppur.2020.117836

Cited by 3 publications

(1 citation statement)

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“…This method gave an extraction of 65% PHB while using a lesser toxic solvent than compared to chloroform. [ 173 ] Ionic liquids, such as 1‐ethyl‐3‐methylimidazolium diethyl phosphate, when used for PHA extraction from H. hydrothermalis resulted in a recovery of 60 ± 2% of the polymer with 86% purity. [ 174 ]…”

Section: Recovery Methods Involved In Pha (Downstream Processing)mentioning

confidence: 99%

Process optimization, metabolic engineering interventions and commercialization of microbial polyhydroxyalkanoates production – A state‐of‐the art review

Lhamo

Behera

Mahanty

2021

Biotechnology Journal

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Background Microbial polyhydroxyalkanoates (PHAs) produced using renewable resources could be the best alternative for conventional plastics. Despite their incredible potential, commercial production of PHAs remains very low. Nevertheless, sincere attempts have been made by researchers to improve the yield and economic viability of PHA production by utilizing low‐cost agricultural or industrial wastes. In this context, the use of efficient microbial culture or consortia, adoption of experimental design to trace ideal growth conditions, nutritional requirements, and intervention of metabolic engineering tools have gained significant attention. Purpose and scope This review has been structured to highlight the important microbial sources for PHA production, use of conventional and non‐conventional substrates, product optimization using experimental design, metabolic engineering strategies, and global players in the commercialization of PHA in the past two decades. The challenges about PHA recovery and analysis have also been discussed which possess indirect hurdle while expanding the horizon of PHA‐based bioplastics. Summary Selection of appropriate microorganism and substrate plays a vital role in improving the productivity and characteristics of PHAs. Experimental design‐based bioprocess, use of metabolic engineering tools, and optimal product recovery techniques are invaluable in this dimension. Conclusion Optimization strategies, which are being explored in isolation, need to be logically integrated for the successful commercialization of microbial PHAs.

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Section: Recovery Methods Involved In Pha (Downstream Processing)mentioning

confidence: 99%