Environmental persistence of chemicals and their carcinogenic risks to humans

Pollack, N.; Cunningham, Albert R.; Rosenkranz, Herbert S.

doi:10.1016/s0027-5107(03)00097-6

Cited by 17 publications

(7 citation statements)

References 62 publications

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“…), secondary consumer (fishes) and microorganisms ( P. putida, Photobacterium phosphoreum, Vibrio fischeri , etc.) (Zeeman et al , 1995; Pollack et al , 2003; Licht et al , 2004). Alternatively, some of the tests make use of specific organisms rather than assessing the toxicity against a number of different test organisms.…”

Section: Assessment Of Soil and Groundwater Ecotoxicitymentioning

confidence: 99%

Integrative approaches for assessing the ecological sustainability ofin situbioremediation

2009

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Application of microbial metabolic potential (bioremediation) is accepted as an environmentally benign and economical measure for decontamination of polluted environments. Bioremediation methods are generally categorized into ex situ and in situ bioremediation. Although in situ bioremediation methods have been in use for two to three decades, they have not yet yielded the expected results. Their limited success has been attributed to reduced ecological sustainability under environmental conditions. An important determinant of sustainability of in situ bioremediation is pollutant bioavailability. Microbial chemotaxis is postulated to improve pollutant bioavailability significantly; consequently, application of chemotactic microorganisms can considerably enhance the performance of in situ degradation. The environmental fate of degradative microorganisms and the ecological consequence of intervention constitute other important descriptors for the efficiency and sustainability of bioremediation processes. Integrative use of culture-dependent, culture-independent methods (e.g. amplified rDNA restriction analysis, terminal restriction fragment length polymorphism, denaturing/thermal gradient gel electrophoresis, phospholipid fatty acid, etc.), computational and statistical analyses has enabled successful monitoring of the above aspects. The present review provides a detailed insight into some of the key factors that affect the efficiency of in situ bioremediation along with a comprehensive account of the integrative approaches used for assessing the ecological sustainability of processes. The review also discusses the possibility of developing suicidal genetically engineered microorganisms for optimized and controlled in situ bioremediation.

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Section: Assessment Of Soil and Groundwater Ecotoxicitymentioning

confidence: 99%

Integrative approaches for assessing the ecological sustainability ofin situbioremediation

2009

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“…Recipient waterways, such as lakes, rivers and coastal areas receive great amounts of industrial, agricultural and urban waste directly via inputs and conveyance as well as indirectly through atmospheric deposition of aerial emissions. A complex mixture of toxic substances with an increasing number of contaminants has been deposited in these waters, posing a threat to aquatic ecosystems as much as to the health and well-being of human populations [5].…”

Section: Water Sustainability As a Resourcementioning

confidence: 99%

Relationship Between Biomarkers and Pesticide Exposure in Fishes: A Review

Ghisi¹

2012

Pesticides - Advances in Chemical and Botanical Pesticides

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“…A study by Pollack et al [58] concerning the relationship between the environmental persistence of xenobiotics and possible health consequences, found significant synergy between hydrophilicity and biodegradability and between lipophilicity and non-biodegradability. Moreover, biodegradability was found to be associated with significant decreases of prevalence of the compounds with the potential to reduce cancer.…”

Section: Organochlorinesmentioning

confidence: 99%

Subject Index to Volume 1

2006

Current Cancer Therapy Reviews

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Breast cancer continues to be worldwide public health concern in America and Western Europe as the commonest cancer among women and the second highest reason of cancer death. Epidemiological evidences implicating environmental and lifestyle risk factors in breast cancer etiology are accumulating. In this review, the current state of knowledge is reviewed, pertaining to relationship between environmental exposures (persistent chemicals, radiation, electromagnetic fields), lifestyle (physical activity, diet, obesity, smoking, alcohol use, oral contraceptive, hormone replacement therapy) and breast cancer risk. This paper also summarises the epidemiological literature on the cellular mechanisms of steroidal estrogens metabolism to carcinogenic products.The epidemiological data have shown that investigation of breast cancer risk among women is difficult to study because of confounding or modification from reproductive female characteristics. Moreover, multiple factors, known as well as unknown, may contribute to the breast cancer development. Through the inconsistencies and contradictions that appear to exist in the literature with respect to the role of environmental and lifestyle factors in genesis of breast cancer, several factors have been identified that are likely to have a major effect on breast cancer risk. Radiation exposure has been a well-defined environmental factor for breast cancer, especially at young ages. The environmental hazard chemicals and electromagnetic fields exposition are discussed as potential mammary carcinogens, but association between those environmental causes and breast cancer risk was not confirmed.Obesity in postmenopausal women and sedentary lifestyle increase the risk of breast cancer. Moderate to high levels of the alcohol consumption, current oral contraceptive use, especially by young women, and prolonged use of hormone replacement therapy causes a moderate increase in the risk of breast cancer.

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Environmental persistence of chemicals and their carcinogenic risks to humans

Cited by 17 publications

References 62 publications

Integrative approaches for assessing the ecological sustainability ofin situbioremediation

Integrative approaches for assessing the ecological sustainability ofin situbioremediation

Relationship Between Biomarkers and Pesticide Exposure in Fishes: A Review

Subject Index to Volume 1

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