Environmental metal contamination and health impact assessment in two industrial regions of Romania

Nedelescu, Mirela; Baconi, Daniela Luiza; Neagoe, Aurora; Iordache, Virgil; Stan, Miriana; Constantinescu, Paula; Ciobanu, Anca Marina; Vardavas, Alexander; Vinceti, Marco; Tsatsakis, Aristidis

doi:10.1016/j.scitotenv.2016.12.053

Cited by 43 publications

(14 citation statements)

References 34 publications

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“…The transfer coefficient was calculated with relation 1 [6,12]: where: Ct is the transfer coefficient; Cfp is the final metal content in the plant (mg kg -1 ); Cis is the initial heavy metal content in the initially contaminated soil (mg kg -1 ).…”

Section: Resultsmentioning

confidence: 99%

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General Tendencies of the Behaviour of Vegetables Developed in a Soil Contaminated with Heavy Metals

Pruteanu¹,

Vlăduț²,

Cârdei³

et al. 2020

Rev. Chim.

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The paper presents experimental results obtained in the study of heavy metals transfer from soil to vegetables. The experiments for which the raw and statistically processed data are presented in this paper are preliminary experiments within an extensive research program of plant behaviour in soils contaminated with heavy metals. These experiments underlie the development of primary statistical mathematical models that are also presented in the paper. These experiments will also form the basis for far more consistent experiments that follow plants throughout the life cycle. The statistical mathematical models presented in this paper facilitate extracting important conclusions about how plants accumulate heavy metals as well as about the accumulation rate behaviour during experiments. Both experiments and mathematical models will form the basis of complex experiments and dynamic mathematical models in the next stage of research.

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Section: Resultsmentioning

confidence: 99%

“…The analyzed vegetables proved to have different capacity of bioaccumulation, depending on plant species, type of metal, type of soil, etc. [6,7,8]. Heavy metals can be readily taken up by vegetable roots, and can be accumulated at high levels in the edible parts of vegetables, even heavy metal in soil at low levels.…”

mentioning

confidence: 99%

General Tendencies of the Behaviour of Vegetables Developed in a Soil Contaminated with Heavy Metals

Pruteanu¹,

Vlăduț²,

Cârdei³

et al. 2020

Rev. Chim.

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“…Industrial regions often have extensive environmental contamination by metals. In Romania, lead, cadmium, copper, and zinc contaminated crops, exceeding maximum acceptable levels in some samples [61]. In China, cadmium from a zinc smelter contaminated leaf and root vegetables particularly [62].…”

Section: Sources Of Contaminants From the Environment To Food Andmentioning

confidence: 99%

Environmental Chemical Contaminants in Food: Review of a Global Problem

Thompson

Darwish

2019

Journal of Toxicology

256

124

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Contamination by chemicals from the environment is a major global food safety issue, posing a serious threat to human health. These chemicals belong to many groups, including metals/metalloids, polycyclic aromatic hydrocarbons (PAHs), persistent organic pollutants (POPs), perfluorinated compounds (PFCs), pharmaceutical and personal care products (PPCPs), radioactive elements, electronic waste, plastics, and nanoparticles. Some of these occur naturally in the environment, whilst others are produced from anthropogenic sources. They may contaminate our food—crops, livestock, and seafood—and drinking water and exert adverse effects on our health. It is important to perform assessments of the associated potential risks. Monitoring contamination levels, enactment of control measures including remediation, and consideration of sociopolitical implications are vital to provide safer food globally.

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“…Toxic metals are further found as a contaminant in fertilizer, which in turn can enter the food cycle [4][5][6]. The effect of toxic metal contamination on crop production has been well documented [6][7][8][9][10][11]. Various studies have shown that the general population is exposed to these chemicals through different sources of exposure [12][13][14][15][16][17].…”

Section: Toxic Metalsmentioning

confidence: 99%

Toxic-Metal-Induced Alteration in miRNA Expression Profile as a Proposed Mechanism for Disease Development

Wallace

Taalab

Heinze

et al. 2020

Cells

111

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Toxic metals are extensively found in the environment, households, and workplaces and contaminate food and drinking water. The crosstalk between environmental exposure to toxic metals and human diseases has been frequently described. The toxic mechanism of action was classically viewed as the ability to dysregulate the redox status, production of inflammatory mediators and alteration of mitochondrial function. Recently, growing evidence showed that heavy metals might exert their toxicity through microRNAs (miRNA)-short, single-stranded, noncoding molecules that function as positive/negative regulators of gene expression. Aberrant alteration of the endogenous miRNA has been directly implicated in various pathophysiological conditions and signaling pathways, consequently leading to different types of cancer and human diseases. Additionally, the gene-regulatory capacity of miRNAs is particularly valuable in the brain-a complex organ with neurons demonstrating a significant ability to adapt following environmental stimuli. Accordingly, dysregulated miRNAs identified in patients suffering from neurological diseases might serve as biomarkers for the earlier diagnosis and monitoring of disease progression. This review will greatly emphasize the effect of the toxic metals on human miRNA activities and how this contributes to progression of diseases such as cancer and neurodegenerative disorders (NDDs).

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Environmental metal contamination and health impact assessment in two industrial regions of Romania

Cited by 43 publications

References 34 publications

General Tendencies of the Behaviour of Vegetables Developed in a Soil Contaminated with Heavy Metals

General Tendencies of the Behaviour of Vegetables Developed in a Soil Contaminated with Heavy Metals

Environmental Chemical Contaminants in Food: Review of a Global Problem

Toxic-Metal-Induced Alteration in miRNA Expression Profile as a Proposed Mechanism for Disease Development

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