Environmental Manipulation: A Potential Tool for Mosquito Vector Control

Christian, Ukubuiwe Azubuike; Kayode, Olayemi Israel; Chinenye, Ukubuiwe Catherine; Sule, Ugbede Bright

doi:10.5772/intechopen.95924

Cited by 3 publications

(3 citation statements)

References 95 publications

(106 reference statements)

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“…Recently, a previous study conducted by our research team revealed a significant positive correlation between larval density and temperature, dissolved oxygen, and salinity in the coastal zone of Benin [11]. Additionally, Ukubuiwe et al [12] found that mosquito larvae can adapt to higher ambient pH levels than other aquatic organisms. In Western Kenya, a study showed a positive correlation between anopheline abundance and nitrate levels in water, while negative but significant correlations were observed with iron levels in water and biofilm cover on the water surface [13].…”

Section: Introductionmentioning

confidence: 73%

Physico-chemical characterization of Anopheles gambiae s.l. breeding sites and kdr mutations in urban areas of Cotonou and Natitingou, Benin

Djègbè,

Hessou-Djossou,

Gounou Boukari

et al. 2024

BMC Infect Dis

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Background This study aimed to investigate the relationship between the physicochemical characteristics of An. gambiae s.s. and An. coluzzii breeding sites, the susceptibility profiles to commonly used insecticides in public health, and the underlying insecticide resistance mechanisms. Methods Anopheles breeding sites surveys were conducted in Cotonou and Natitingou in September 2020, January and August 2021. Physicochemical properties and bacterial loads were determined in individual breeding sites. The WHO susceptibility assays were carried out using the female of the emerging adult mosquitoes. Anopheles species were identified through PCR techniques. Kdr L1014F/S, N1575Y and G119S mutations were investigated using TaqMan genotyping assays. Results Molecular analysis showed that all mosquitoes analyzed in Cotonou were Anopheles coluzzii, while those of Natitingou were Anopheles gambiae s.s. Fecal coliforms were identified as playing a role in this distribution through their significant influence on the presence of An. coluzzii larvae. WHO susceptibility assay indicated a high level of resistance to deltamethrin in the two cities. The resistance levels to deltamethrin were higher in Cotonou (X2 = 31.689; DF = 1; P < 0.0001). There was a suspected resistance to bendiocarb in Cotonou, whereas the mosquito population in Natitingou was resistant. The kdr L1014F mutation was highly observed in both mosquito populations (frequence: 86–91%), while the Ace-1 mutation was found in a small proportion of mosquitoes. In Cotonou, salinity was the only recorded physicochemical parameter that significantly correlated with the resistance of Anopheles mosquitoes to deltamethrin (P < 0.05). In Natitingou, significant correlations were observed between the allelic frequencies of the kdr L1014F mutation and pH, conductivity, and TDS. Conclusion These results indicate a high level of pyrethroid resistance in the anopheles populations of both Cotonou and Natitingou. Moreover, this study report the involvement of abiotic factors influencing Anopheles susceptibility profile.

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Section: Introductionmentioning

confidence: 73%

Physico-chemical characterization of Anopheles gambiae s.l. breeding sites and kdr mutations in urban areas of Cotonou and Natitingou, Benin

Djègbè,

Hessou-Djossou,

Gounou Boukari

et al. 2024

BMC Infect Dis

View full text Add to dashboard Cite

show abstract

“…Recently, a previous study conducted by our research team revealed a signi cant positive correlation between larval density and temperature, dissolved oxygen, and salinity in the coastal zone of Benin [11]. Additionally, Ukubuiwe et al [12] found that mosquito larvae can adapt to higher ambient pH levels than other aquatic organisms. In Western Kenya, a study showed a positive correlation between anopheline abundance and nitrate levels in water, while negative but signi cant correlations were observed with iron levels in water and bio lm cover on the water surface [13].…”

Section: Introductionmentioning

confidence: 75%

Characterization of Anopheles gambiae breeding sites and insecticide resistance mechanisms in urban areas of Cotonou and Natitingou, Benin

Djègbè,

HESSOU-DJOSSOU,

Boukari

et al. 2023

Preprint

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Background This study aimed to investigate the relationship between the physicochemical characteristics of An. gambiae and An. Coluzzii breeding sites, the susceptibility to common insecticides used in public health, and the underlying insecticide resistance mechanisms. Methods Anopheles breeding sites surveys were conducted in Cotonou and Natitingou. Physicochemical parameters and bacterial loads were determined in individual breeding sites. The WHO susceptibility assays were carried out using the female of the emerging adult mosquitoes. Anopheles species were identified through PCR techniques. Kdr L1014F/S, N1575Y and G119S mutations were investigated using TaqMan genotyping assays. Results Molecular analysis showed that all mosquitoes analyzed in Cotonou were Anopheles coluzzii, while those of Natitingou were Anopheles gambiae s.s. WHO susceptibility assay indicated a high level of resistance to deltamethrin in the two cities. The resistance levels to deltamethrin were higher in Cotonou (X2 = 31.689; DF = 1; P < 0.0001). There was a suspicion of resistance to bendiocarb in Cotonou, whereas the mosquito population in Natitingou was resistant. The kdr L1014F mutation was highly observed in both mosquito populations, while the Ace-1 mutation was found in a small proportion of mosquitoes. In Cotonou, salinity was the only recorded physicochemical parameter significantly correlated with the resistance of Anopheles mosquitoes to deltamethrin. In Natitingou, significant correlations were observed between the allelic frequencies of the kdr L1014F mutation and pH, conductivity, and TDS. Conclusion These results indicate a high level of pyrethroid resistance in the An. gambiae population of both Cotonou and Natitingou. Moreover, the data suggest the involvement of the kdr mutation and possibly the breeding sites abiotic factors.

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“…Both processes enable insects to either avoid or shorten interaction with the hazardous compound. Comparing behavioural resistance to biochemical insensitivity and resistance by changing the appropriateness accuracy of insecticides, it is more challenging to monitor field populations and use relatively simple exposure assays, which contributes to the scarcity of data on behavioural resistance [15] .…”

Section: Variation In Their Ecology Changes In the Behavior And Avoid...mentioning

confidence: 99%

Biological control of the mosquito: An analysis of the impediments and possibilities

Singh,

Kumar,

Kumar

et al. 2023

Int. J. Mosq. Res.

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Biological control of mosquito is an eco-friendly approach for the control of some vector borne diseases. Numerous tools have been developed and applied to scale down the mosquito population, but the ultimate goal of these different strategies is only to mitigate the menace of mosquito and effectively prevent malaria like diseases. Unfortunately, most of these vectors control measurement the time limited prevention of diseases. For example, they were used as an insecticide, but insecticide resistant mosquito vectors are developed in course of time. Major efforts may be focused on generating eco-friendly alternatives. In current scenario there are many potential alternatives for eradicating and controlling the mosquito vectors biologically. Effective use of aquatic insect predators, larvivorous fishes, symbiotic bacteria, microbial agent and entopathogenic fungi for this purpose are still rather unexplored calling for further research. Biological control of mosquito vectors has been validated for several advantages over insecticides. To resolve the problem of current dependence on insecticidal-based mosquito elimination the option of biological control of this vector is ecofriendly and sustainable. The current knowledge of bio-controlling agents highlighting its significance in the field of public health with respective have been reviewed in this article along with the prospective challenges and opportunities.

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Environmental Manipulation: A Potential Tool for Mosquito Vector Control

Cited by 3 publications

References 95 publications

Physico-chemical characterization of Anopheles gambiae s.l. breeding sites and kdr mutations in urban areas of Cotonou and Natitingou, Benin

Physico-chemical characterization of Anopheles gambiae s.l. breeding sites and kdr mutations in urban areas of Cotonou and Natitingou, Benin

Characterization of Anopheles gambiae breeding sites and insecticide resistance mechanisms in urban areas of Cotonou and Natitingou, Benin

Biological control of the mosquito: An analysis of the impediments and possibilities

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