Introduction: Environmental determinants are integral part of etiology, severity and management of asthma. But the association between various indoor and outdoor triggers with pediatric asthma has been inconsistent, complex and variable across the globe. This study was aimed at identifying the environmental risk factors associated with childhood asthma in our region. Methods: This was a hospital-based cross-sectional study done at Perundurai Medical college hospital, Tamilnadu. After getting Institutional Ethical Committee approval, children in the age group of 2 to 15 years attending the pediatric outpatient department were enrolled in the study. Parents were interviewed with ISAAC questionnaire and history of exposure to various indoor and outdoor triggers was recorded in addition to the basic demographic details and anthropometric indices. Data was analyzed using Chi-square tests and logistic regression analysis.