Environmental contaminants and human health in the Canadian Arctic

Donaldson, Shawn G.; Oostdam, Jay Van; Tikhonov, Constantine; Feeley, Mark; Armstrong, B; Ayotte, Pierre; Boucher, Olivier; Bowers, Wayne J.; Chan, Laurie; Dallaire, Frédéric; Dallaire, Renée; Dewailly, Éric; Edwards, John W.; Egeland, Grace M.; Fontaine, J.; Furgal, Chris; Leech, Tara; Loring, E.; Muckle, Gina; Nancarrow, T.; Pereg, Daria; Plusquellec, Pierrich; Potyrala, Mary; Receveur, Olivier; Shearer, Russel

doi:10.1016/j.scitotenv.2010.04.059

Cited by 233 publications

(189 citation statements)

References 275 publications

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“…These findings are supported by an experimental study that showed a link between exposure to POP and insulin resistance, visceral obesity, and glucose intolerance (Ibrahim et al 2011). High concentrations of POP in blood have been reported for northern Indigenous populations (Donaldson et al 2010). Traditional food, in particular fish, is considered the major source of exposure to POP (Seabert et al 2014).…”

Section: Introductionmentioning

confidence: 62%

Fish consumption is inversely associated with type 2 diabetes in Manitoba First Nations communities

Marushka

Batal

Sharp

et al. 2017

FACETS

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Consumption of fish and n-3 fatty acids (n-3 FAs) has been postulated to prevent type 2 diabetes (T2D). Objective: To explore the association between self-reported T2D and fish consumption, dietary n-3 FAs, and persistent organic pollutants (POP) intake in a regionally representative sample of First Nations (FNs) in Manitoba. Design: Data from the cross-sectional First Nations Food, Nutrition and Environment Study (FNFNES) collected from 706 members of 8 Manitoba FNs in 2010 were used. Household interviews were used to collect social and lifestyle data. The consumption of fish was estimated using a traditional food frequency questionnaire. Fish samples were analyzed for the presence of POP. Multiple logistic regression models adjusted for potential risk factors for T2D were developed. Results: A negative, dose-response relationship was found between fish intake and self-reported T2D. Fish consumptions of 2-3 portions per month and ≥1/week were inversely associated with T2D with odds ratio (OR) values of 0.51 (95% CI: 0.28-0.91) and 0.40 (95% CI: 0.19-0.82), respectively, compared with no fish intake. Similarly, intake of n-3 FAs was negatively associated with T2D (OR = 0.48 (95% CI: 0.30-0.77). Dietary POP intake was not associated with T2D. Conclusion: These findings suggest that the consumption of traditionally harvested fish may have a beneficial effect on T2D in Manitoba FNs.

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Section: Introductionmentioning

confidence: 62%

Fish consumption is inversely associated with type 2 diabetes in Manitoba First Nations communities

Marushka

Batal

Sharp

et al. 2017

FACETS

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“…Research on polar bears is prominent (Stirling and Parkinson 2006;Regehr et al 2007;Crompton et al 2008;Durner et al 2009), along with permafrost (Gough and Leung 2002;Smith et al 2005), caribou populations (Tews et al 2007;Sharma et al 2009), contaminants (Constant et al 2007;Hare et al 2008;Kuzyk et al 2010), and storms Hanesiak et al 2010). Fewer studies have been led by researchers from the health sciences (n = 13, 11 %) but in recent years scholarship has begun to integrate a climate element into longstanding issues such as mental health, food-and waterborne contaminants, food and water security, community infrastructure vulnerability, and hazard planning (Furgal and Seguin 2006; Martin et al 2007;Donaldson et al 2010;Nancarrow and Chan 2010).…”

Section: Research Conducted By the Social And Biophysical Sciences Ismentioning

confidence: 99%

Mapping Human Dimensions of Climate Change Research in the Canadian Arctic

Ford

Bolton

Shirley

et al. 2012

AMBIO

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“…Several neurological and neurobehavioral changes attributed to lead exposure were reported in countries with high lead pollution levels [19][20][21]. It causes learning impairment, lower IQ scores, increased school failure [22,23].…”

Section: Prenatal Exposure To Leadmentioning

confidence: 99%

Prenatal Exposures to Environmental Agents or Drugs Promote the Development of Diseases Later in Life

Tchernitchin¹,

Gaete²

2015

Biol Med (Aligarh)

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Prenatal or early postnatal exposure to several agents displaying hormonal action causes persistent quantitative and qualitative changes in hormone receptors in various cell-types. Exposure must occur during the windows of susceptibility, which occurs at specific times for each cell-type and hormone receptor. These alterations, that persist through life, are induced by the mechanism of epigenetic imprinting (cell programming). Studies performed in our Labs and elsewhere found that not only hormones or agents displaying hormone action, but also those not displaying this activity, may induce the mechanism of imprinting; among them, lead and arsenic.

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Environmental contaminants and human health in the Canadian Arctic

Cited by 233 publications

References 275 publications

Fish consumption is inversely associated with type 2 diabetes in Manitoba First Nations communities

Fish consumption is inversely associated with type 2 diabetes in Manitoba First Nations communities

Mapping Human Dimensions of Climate Change Research in the Canadian Arctic

Prenatal Exposures to Environmental Agents or Drugs Promote the Development of Diseases Later in Life

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