Environmental Applications and Bio-Profiling of <i>Tribulus Terrestris</i>: an Ecofriendly Approach

Abstract

The antibacterial and antioxidant activity of different parts of Tribulus terrestris, such as leaves and roots, was carried out using methanol and n-hexane as solvents. The leaves of plant have greater extraction yield than roots. The antibacterial activity was checked against both gram positive bacteria (Staphylococcus aureus) and gram negative bacteria (Escherichia coli). Antibacterial activity was performed by disk inhibition method. Leaves show greater antibacterial activity (29 mm and 30 mm) against both S. aureus and E. coli, whereas roots show (16 mm and 21 mm) against both species respectively. Antioxidant activity was carried out by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging free-radical assay. Leaf extract showed greater antioxidant activity (73%) than that of roots (52%). Total phenolic content (TPC) and total flavonoid content (TFC) were determined by spectrophotometer analysis. The results indicate that leaf extract contains higher phenolic and flavonoid contents (723 mg Gallic acid equivalents (GAE)/g and 476 mg Quercetin equivalents (QE)/g as compared to roots extract (235mg GAE/g and 93 mg QE/g).

Bioactive Compounds, Antioxidant, Anti-Inflammatory, Anti-Cancer, and Toxicity Assessment of Tribulus terrestris—In Vitro and In Vivo Studies

“…In the present study, it can be stated that higher antioxidant activity of T. terrestris methanol extract in all three assays is due to the presence of the phenolic and flavonoid contents. Lately, a direct relation between total phenolic contents and antioxidant activity has been shown by Arshad et al (2020) [ 44 ]. In brief, the leaves of methanol extract of T. terrestris outlined 73% inhibition in the DPPH assay as compared to 52% inhibition of root extract, which also offered more affinity towards total phenolic (723 mg GAE/g) and flavonoid (476 mg QE/g) extraction than root extract recorded with total phenolic and flavanoid contents of 235 mg GAE/g, and 93 mg QE/g, respectively.…”

Antioxidant Potential and Phenolic Contents of Various Flaxseed Cultivars from Different Agro-Industrial Regions

“…Plants have an abundance of natural antioxidant compounds (secondary metabolites), which consists of variety of phytochemicals. Studies revealed that consumption of diet rich in antioxidants reduced the cardiovascular disease, neurodegenerative disease and cancer incidences [6][7][8]. The phenolic compounds have promising potential in health as nutritional supplements, herbal medicines and ROS-related disease as chemo preventive agents.…”

Synthesis of Silver Nanoparticle from <i>Allium sativum</i> as an Eco-Benign Agent for Biological Applications

“…But when concentration increase from 20 to 40 mg/mL the viability of brines shrimps also decreased up to 60%, it is concluded that some bioactive compounds bind with silver particle and easily cross the cell lining and reduces the viability of larvae. The plants were good candidate for anti-cancer research on the basis of their behavior of toxicity to brine shrimp [1,12,[22][23][24].…”

“…This attribute of garlic is because of so many properties with biological application that have been reported. These properties may include antimicrobial, antioxidant, immunomodulatory, anticancer, antiinflammatory, hypoglycemic and cardiovascular effects [1][2][3]. One of the most plenteous class of organosulfur compounds, present in recently sliced or crumpled garlic is found to be responsible for the health benefits associated with garlic consumption.…”

“…Furthermore, the role of a garlic has been wonderful for the treatment of many diseases especially the most treacherous one i.e., heart disease and cancer. Garlic extract protects oxidative DNA damage due to its significant antioxidant potential [1,2]. Moreover, it decreases the radiation sensitivity of regular skins in the vicinal parts of tumors [9].…”