Environmental and occupational respiratory diseases – 1040. Associations between asthma and bronchial hyper-responsivness with allergy and atopy phenotypes in urban black South African teenagers

Abstract

Levin et al.: Environmental and occupational respiratory diseases-1040. Associations between asthma and bronchial hyper-responsivness with allergy and atopy phenotypes in urban black South African teenagers.

Association between pro‐inflammatory alleles and allergic phenotypes in Xhosa adolescents

“…Skin prick tests (SPTs) to common aero‐ and food allergens (all ALK‐Abello ® except for potato, which was a freshly prepared extract), blood samples for total IgE and A. lumbricoides ‐specific IgE, and a modified methacholine challenge for BHR were performed. The method for this modified challenge has been previously published by our group and is based on the Protocol by Yan et al …”

“…As in many other developing countries, the prevalence of allergic disease in South Africa seems to be increasing . Allergic disease is more prevalent in urban than rural populations and in white than black African subjects; however, the gradient between these populations has narrowed over time . Additionally, there has been a disproportionate increase in both house dust mite (HDM) sensitization and bronchial hyper‐responsiveness (BHR) in recently urbanized children of black African origin .…”

Bronchial Hyperresponsiveness, Word Descriptors, and Ethnicity: Women with Mild Asthma

“…The presence of both increased atopy and nocturnal awakenings for Asian-PI women warrants further exploration (Figures 1 and 2 the degree of atopy with BHR in AFAM teenagers (27) and noted an association between allergic rhinitis and BHR. However, studies of adult asthmatics that examine the relationship between atopy and dose of McH are lacking.…”

SCREENING FOR FOOD SPECIFIC IgE ANTIBODIES AMONG SAUDI PATIENTS WITH CLINICAL SUSPICION OF FOOD ALLERGY.

“…[5] Although a wide variety of foods have been linked with food allergy the most frequently sensitizing food materials include egg, milk, fish, wheat, peanut and soy. [6,7] Regional disparity among sensitizing food allergens is frequently observed. Egg, peanut and wheat are common sensitizing foods in Morocco [8] whereas allergic sensitization due to peanut and pineapple is frequently observed in Ghana.…”