Environmental and Genetic Determinants of Ankylosing Spondylitis
Rafał Bilski,
Piotr Kamiński,
Daria Kupczyk
et al.
Abstract:Exposure to heavy metals and lifestyle factors like smoking contribute to the production of free oxygen radicals. This fact, combined with a lowered total antioxidant status, can induce even more damage in the development of ankylosing spondylitis (AS). Despite the fact that some researchers are looking for more genetic factors underlying AS, most studies focus on polymorphisms within the genes encoding the human leukocyte antigen (HLA) system. The biggest challenge is finding the effective treatment of the di… Show more
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