Environmental allergens and asthma in urban elementary schools

Amr, Sania; Bollinger, Mary E.; Myers, Monica F.; Hamilton, Robert G.; Weiss, Sheila R.; Rossman, Maura; Osborne, Lisette; Timmins, Sidey; Kimes, D. S.; Levine, Elissa R.; Blaisdell, Carol J.

doi:10.1016/s1081-1206(10)63611-3

Cited by 85 publications

(95 citation statements)

References 43 publications

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“…Thirty-three percent of children in this study had guardian-reported asthma, which is three times the national prevalence rate of 10% [9,28] and statewide asthma prevalence of 10.6% [29]. This rate is also higher than the 20% asthma prevalence rate in some inner-city Baltimore schools for children from the same catchment area [9].…”

Section: Discussionmentioning

confidence: 69%

“…This rate is also higher than the 20% asthma prevalence rate in some inner-city Baltimore schools for children from the same catchment area [9]. Data were obtained from a clinical questionnaire that was not validated at the time of this study.…”

Section: Discussionmentioning

confidence: 89%

“…However, the majority of the clinical questions were similar to that used in the BASS questionnaire, which is a 50-item validated questionnaire for OSA screening in children [27]. Asthma "yes" as a listed diagnosis on school emergency forms, albuterol or inhaled steroid was a method used in a previous study for case definition of asthma in Baltimore children [9].…”

Section: Discussionmentioning

confidence: 99%

“…The questionnaire included patient demographics, the patient's past medical history (including asthma), medication use, sleep, and daytime behaviors. Asthma case definition was determined by an answer of "yes" asthma (item 1), as a listed diagnosis (item 2), or asthma related medication use (item 3, General Medical Information-Appendix) as previously used in Baltimore children [9]. Medical insurance information was available from hospital intake data.…”

Section: Study Samplementioning

confidence: 99%

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Obstructive sleep apnea and history of asthma in snoring children

et al. 2008

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Asthma has been identified as a possible risk factor for Obstructive Sleep Apnea (OSA) in children. It is not known whether parent-reported asthma increases the likelihood of the diagnosis of OSA in snoring children. We hypothesized that snoring children with asthma are more likely to have OSA than snoring children without asthma. This study is a 1-year retrospective review of polysomnogram and questionnaire data collected on 236 patients referred to the University of Maryland Pediatric Sleep laboratory for evaluation of snoring. Of the 236 patients, 58% (137/236) were boys, and 79% (173/219 reporting race) were African-American (AA). The age at referral was 7.2±3.7 years (mean±S.D.). Mean body mass index (BMI) percentile was 73.4±32.3%, with 43.2% (54/125) >95th percentile. A history of asthma was reported by 31.4% (74/ 236); no subject was symptomatic on the night of the study. We found no increased risk for polysomnographically diagnosed OSA for asthmatics. To the contrary, by logistic regression analysis, a parent/guardian report of asthma decreased the odds of having OSA by 34% (p=0.027), controlling for individual and socioeconomic factors and assessment results. Polysomnographic (PSG) differences between asthmatic and non-asthmatic children were found in only the arousal index (11.0 vs.9.3±6.5/h, p=0.099) and total sleep time (337.1± 64.3 vs. 347±65.2 min, p=0.1) In a referral-based group of predominantly AA inner-city snoring children, asymptomatic asthma decreased the likelihood of OSA.

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Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Study Samplementioning

confidence: 99%

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Obstructive sleep apnea and history of asthma in snoring children

et al. 2008

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“…Cat and dog allergen levels have generally been found in higher levels in carpeted and upholstered areas. 13,16,24,26 However, this relationship with carpeted floor was not present in all studies. 11 Although mite levels tend to exhibit seasonal fluctuations that parallel those in ambient relative humidity, additional factors, including human activities and heating, ventilation, and air conditioning may also influence indoor air humidity levels.…”

Section: Distributions Of Allergensmentioning

confidence: 81%

An Important Source for Cat and House Dust Mite Allergens: Day-Care Centers

GÜLBAHARAssoc.¹,

Korkmaz²,

Erdem³

et al. 2012

Turkiye Klinikleri J Med Sci

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A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : Exposure to indoor allergens during childhood has been associated with an increased risk of sensitization. There is no data about indoor allergen levels in day-care centers in Turkey. We hypothesized that day-care centers (DC) would be relevant sources of cat and mite allergens. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Fifty-seven dust samples were collected from 19 DCs in İzmir, their gardens, and classrooms of the primary schools where the DCs are located in. A questionnaire about characteristics of DCs was completed. Fel d 1, Der p 1 and Der f 1 allergen levels were quantitated by enzyme-linked immunoassay. R Re es su ul lt ts s: : Fel d 1 was detected in all, and mite allergens in 94.7% of the samples. Levels exceeding sensitization threshold level for cat and mite allergens were present in 73.7%, and 21.1% of DCs, respectively. Fel d 1 levels exceeding threshold level that might cause asthma exacerbation was detected in 21% of DCs. Fel d 1 levels in DCs and their gardens were higher than the classrooms of the same school. Der f 1 levels were identical in DCs, gardens and classrooms. Der p 1 concentration was higher in DCs with air-conditioning, than DCs without a ventilation system. Although there was no difference for Fel d 1 levels in DCs with or without carpeted floor, Fel d 1 concentrations in DCs with carpet were significantly higher than in classrooms with no carpet. C Co on nc cl lu us si io on n: : Day-care centers in İzmir are important sources of indoor allergens that could cause sensitization or even allergic symptoms in children and their staff.

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