Environmental acidification triggers oxidative stress and enhances globin expression in zebrafish gills

Evaluation of the estrogenic and oxidative stress effects of the UV filter 3-benzophenone in zebrafish (Danio rerio) eleuthero-embryos

“…Results regarding transcriptional changes of antioxidant enzymes has produced contrasted results, for example, some authors have found that during exposures to different stressors transcription was up-regulated (e.g. Li et al, 2013;Tiedke et al, 2013;Jin et al, 2010;Henrik Hansen et al, 2007). On the contrary, others have found down-regulation of these genes (e.g.…”

Temperature and acidification variability reduce physiological performance in the intertidal zone porcelain crabPetrolisthes cinctipes

“…pH stress), resulting in crosstolerance (Kültz, 2005). Acidification has been shown to induce CSR heat shock proteins hsp70 and hsp90 in gill tissue of zebrafish, demonstrating that cellular responses to acidification share signaling pathways and cross-talk with cellular responses to thermal stress (Sinclair et al, 2013;Tiedke et al, 2013). Even without clear mechanisms, the observed decreases in metabolism combined with increased upper temperature tolerance (i.e.…”

Effects of prolonged exposure to low pH on enzymatic and non-enzymatic antioxidants in Japanese Medaka (Oryzias latipes)

“…For example, enhanced Mn-superoxide dismutase and GPx gene expression was observed in Tilapia blood cells after acute exposure (36 h) to pH 5.3 (Mai et al, 2010). In Zebrafish (Danio rerio), acute exposure to pH 4.0 induced increased superoxide dismutase, catalase and GPx mRNA expression in gills and the whole fish (Tiedke et al, 2013). On the other hand, absence of changes in GPx and GCL gene expression in the current study implies that differences in GPx activity and total glutathione concentration, respectively, were not caused by gene downregulation at higher pH levels.…”

“…Acute and sublethal effects of acidification of freshwater ecosystems on fish physiology, including increased permeability of gill membrane with consequent disruption of ion regulation, changes in swimming pattern, decreased activity, reduced growth, ventilation problems, deformations, bone malformations such as scoliosis and lordosis, and decline in spawning frequency and hatching success have been reported (Sparling, 1995). In addition, a short exposure to low pH has induced increased production of reactive oxygen species (ROS) and changes in the levels of antioxidants (Carvalho et al, 2015;Mai et al, 2010;Tiedke et al, 2013). However, little is known about long-term effects on the oxidant/ antioxidant balance and oxidative damage in chronically acidified freshwater ecosystems.…”

“…To our knowledge, studies to date have assessed pH effects on antioxidant systems and oxidative damage using acute exposures (Carvalho et al, 2015;Mai et al, 2010;Tiedke et al, 2013), however little is known about how prolonged exposure to low pH affect antioxidant defense systems and potentially promotes oxidative stress in fish. Promoting our understanding of impacts or adverse effects on fish by prolonged exposure helps us develop criteria for protecting fragile acidified freshwater ecosystems (e.g.…”