“…Thus, NE prevalence varies markedly among countries and regions within countries, reflecting socioeconomic differences, educational levels, heredity factors, and inclusion criteria. Consistent with most studies, overall prevalence was greater in boys [2,6,12,13,19], about a quarter of cases were SNE, and prevalence decreased with age. It is critical to identify underlying correlative secondary diseases, such as phimosis, urinary tract infection, spina bifida occulta (SBO), and psychological stressors.…”