“…Trehalose, sorbitol, ectoine, mannitol, and betaine induce increases in the pre-nucleation slope in comparison to the relative reference experiments at both pH values. At pH 9.0, this corresponds to percentage increases of about 87,44,29,26, and 20%, respectively. At higher pH (9.75), these effects are more pronounced, leading to corresponding increases of about 41,56,66,109, and 39% in the pre-nucleation slope.…”