Entorhinal cortical lesions in rats and runway alternation performance: changes in patterns of response initiation

Engelhardt, F.; Steward, Oswald

doi:10.1016/s0163-1047(80)92512-1

Cited by 9 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have observed a similar increase in the area of the dentate gyrus using an acetylcholinesterase stain following aspiration lesions of the EC like those used in the present research (unpublished results, 1995). Although there are many problems associated with assessing any functional correlates of the regrowth (see Engelhardt & Steward, 1980), it is possible that the facilitated conditioning found following EC lesions could have such an anatomical basis.…”

Section: Discussionmentioning

confidence: 99%

Facilitation of conditioned odor aversion by entorhinal cortex lesions in the rat.

Ferry¹,

Oberling²,

Jarrard³

et al. 1996

Behavioral Neuroscience

View full text Add to dashboard Cite

This study examined the role of the entorhinal cortex (EC) in conditioned odor aversion learning (COA). Lateral EC lesions did not impair but rather facilitated COA. In the experiments the delay separating the odor cue presentation from the subsequent toxicosis was varied during acquisition. EC-lesioned rats demonstrated COA for delays up to 2 hr, whereas sham-operated rats displayed COA only if toxicosis immediately followed the odor cue. This facilitation was not dependent on the intensity of the odor and corresponded to a facilitated long-delay learning. EC lesion did not affect conditioned taste aversion, confirming that the facilitation effect does not correspond to a general facilitation of conditioned aversion learning. Taken together, these results indicate that the removal of the EC may allow odor-toxicosis associations across longer delays by extending the duration of the olfactory trace.

show abstract

Section: Discussionmentioning

confidence: 99%