Enterovirus Surveillance - United States, 1970-2005

Khetsuriani, Nino; Lamonte-Fowlkes, Ashley; Oberst, Steven; Pallansch, Mark A.

doi:10.1037/e540562006-001

Cited by 439 publications

(626 citation statements)

References 112 publications

Supporting

Mentioning

520

Contrasting

Unclassified

Order By: Relevance

“…Enteroviruses, members of the Picornaviridae family, are among the most common human-infecting viruses worldwide [1]. They are associated with several human diseases that cause a wide range of clinical syndromes, such as the common cold; hand, foot, and mouth disease (HFMD); acute flaccid paralysis; acute hemorrhagic conjunctivitis; aseptic meningitis; and myocarditis [2,3].…”

Section: Introductionmentioning

confidence: 99%

Development of Loop-Mediated Isothermal Amplification (LAMP) for Universal Detection of Enteroviruses

et al. 2013

View full text Add to dashboard Cite

Enteroviruses are found in most environments and cause several diseases in humans. Loop-mediated isothermal amplification (LAMP) was adapted and evaluated for the rapid detection of enteroviruses. Based on the highly conserved 5 0 untranslated region (5 0 -UTR) of the human enteroviruses (HEVs), particularly human enterovirus A (HEV-A) and HEV-B, a set of universal primers was designed. The LAMP amplification was carried out under isothermal conditions at 61°C, depending on the template concentration results were obtained within 45-90 min. The detection limits were found to be 10 1 copies of cloned enterovirus 71 fragments, more sensitive than conventional PCR. Nine water samples collected from drinking water sources during three seasons and 19 stool specimens collected from HFMD patients were analyzed. By using the LAMP assay, the majority of samples was tested positive, 9/9 (100 %) and 18/19 (94.7 %), respectively. LAMP is a practical method for the rapid detection of enteroviruses in environmental and clinical samples.

show abstract

Section: Introductionmentioning

confidence: 99%

Development of Loop-Mediated Isothermal Amplification (LAMP) for Universal Detection of Enteroviruses

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Coxsackievirus B (CVB) 3 infection is commonly associated with myocarditis (2). Although myocarditis is increased in men, rates of infection with CVB are similar between men and women worldwide (3)(4)(5). The lower incidence of heart disease in women has been attributed to the cardioprotective effects of estrogen (6).…”

mentioning

confidence: 99%

Cutting Edge: Cross-Regulation by TLR4 and T cell Ig Mucin-3 Determines Sex Differences in Inflammatory Heart Disease

Frisancho-Kiss

Davis

Nyland

et al. 2007

The Journal of Immunology

188

271

View full text Add to dashboard Cite

Recent clinical studies have reinforced the importance of sex-related differences in the pathogenesis of cardiovascular diseases, with an increased incidence and mortality in men. Similar to humans, male BALB/c mice infected with coxsackievirus B3 (CVB3) develop more severe inflammation in the heart even though viral replication is no greater than in females. We show that TLR4 and IFN-γ levels are significantly elevated and regulatory T cell (Treg) populations significantly reduced in the heart of males following CVB3 infection, whereas females have significantly increased T cell Ig mucin (Tim)-3, IL-4 and Treg. Blocking Tim-3 in males significantly increases inflammation and TLR4 expression while reducing Treg. In contrast, defective TLR4 signaling significantly reduces inflammation while increasing Tim-3 expression. Cross-regulation of TLR4 and Tim-3 occurs during the innate and adaptive immune response. This novel mechanism may help explain why inflammatory heart disease is more severe in males.

show abstract

“…As for viruses of the family Picornaviridae, viruses of different genera have different seasonal patterns of activity. For example, enteroviruses are more active during the summer months, whereas rhinoviruses usually have spring and autumn peaks (Khetsuriani et al, 2006;Monto, 2002). In this study, almost all TV1, TV2 and TV3 were found in November, December and January.…”

Section: P C Y Woo and Othersmentioning

confidence: 67%

Comparative analysis of six genome sequences of three novel picornaviruses, turdiviruses 1, 2 and 3, in dead wild birds, and proposal of two novel genera, Orthoturdivirus and Paraturdivirus, in the family Picornaviridae

Woo

Lau

Huang

et al. 2010

Journal of General Virology

View full text Add to dashboard Cite

Enterovirus Surveillance - United States, 1970-2005

Abstract: depar depar depar depar department of health and human ser tment of health and human ser tment of health and human ser tment of health and human ser tment of health and human services vices vices vices vices

Cited by 439 publications

References 112 publications

Development of Loop-Mediated Isothermal Amplification (LAMP) for Universal Detection of Enteroviruses

Development of Loop-Mediated Isothermal Amplification (LAMP) for Universal Detection of Enteroviruses

Cutting Edge: Cross-Regulation by TLR4 and T cell Ig Mucin-3 Determines Sex Differences in Inflammatory Heart Disease

Comparative analysis of six genome sequences of three novel picornaviruses, turdiviruses 1, 2 and 3, in dead wild birds, and proposal of two novel genera, Orthoturdivirus and Paraturdivirus, in the family Picornaviridae

Contact Info

Product

Resources

About