“…While recognizing the potential benefits of such programmes for subsets of patients (see below), several researchers and practitioners felt that the growing evidence of ongoing pathology supported the view that internal cues might well signal the need for protective action [23,[34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50]. Accordingly, pacing encourages the person with ME/CFS to recognize discomfort and to not 'push' themselves, in order to prevent an exacerbation of symptoms.…”