Enteritis Cystica Profunda: Is Trauma the Etiology? Interval Development in the Previously Normal Ileum: A Case Report and Literature Review

Abstract

Although well described in the colon, enteritis cystica profunda is an extremely rare lesion of the small intestine with only a few cases documented in English medical literature. It is a benign condition most often associated with Crohn's disease or Peutz-Jeghers syndrome in the adult. It has been described presenting as ileoileal intussusception in the pediatric population. We report a case of enteritis cystica profunda found incidentally on exploratory laparotomy with evidence of interval development over a 5-month period confirming trauma as the etiology.

Enteritis Cystica Profunda Presenting as Recurrent Sub Acute Intestinal Obstruction-NOT ALL Cases of IC Strictures are Koch’s! A Case Report

“…They can be formed anywhere in the gastrointestinal tract but most commonly in the large intestine, in which case it is called colitis cystica profunda, first described by Virchow in 1863. The etiology is thought to be mucosal or submucosal damage, and hence high incidence is seen in diseases with mucosal ulceration or inflammation of submucosa such as ulcerative colitis, dysentery, Crohn's disease, adenomatous polyposis, Peutz-Jeghers syndrome, and also trauma [3][4][5]7]. Hypothesis of congenital origin is supported by findings of submucosal cysts in various parts of the gastrointestinal tract.…”

Enteritis cystica profunda with lipoma in the second portion of the duodenum: a case report

“…ECP occurs mainly in the ileum or jejunum and is related to diseases such as Crohn disease and Peutz-Jeghers syndrome [2][3][4][5][6][7][8][9][10][11][12][13][14]. ECP also develops without associated conditions [15][16][17][18][19][20]. ECP in the duodenum is rare and mostly occurs without an associated pathological condition, unlike ECP in the ileum or jejunum [15][16][17][18].…”

“…ECP also develops without associated conditions [15][16][17][18][19][20]. ECP in the duodenum is rare and mostly occurs without an associated pathological condition, unlike ECP in the ileum or jejunum [15][16][17][18]. So far, there have been only six reports on ECP in Korea [2,3,[15][16][17][18].…”

“…ECP in the duodenum is rare and mostly occurs without an associated pathological condition, unlike ECP in the ileum or jejunum [15][16][17][18]. So far, there have been only six reports on ECP in Korea [2,3,[15][16][17][18]. One report described a case of ECP coexisting with lipoma in the duodenal bulb [18].…”

“…So far, there have been only six reports on ECP in Korea [2,3,[15][16][17][18]. One report described a case of ECP coexisting with lipoma in the duodenal bulb [18]. In the foreign literature also, ECP cases are rare, and only one case of ECP coexisting with lipoma in the ileum has been reported [4][5][6][7][8][9][10][11][12]19].…”