Enteritis associated with infection by Campylobacter jejuni in two Thoroughbred foals

Blunden, A. S.; Smith, Ken; Neal, H. N.; Dugdale, D. J.

doi:10.1111/j.2042-3292.2006.tb00404.x

Cited by 4 publications

(4 citation statements)

References 10 publications

(13 reference statements)

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“…Others have tried to specifically identify populations by culturing specific species from foals in the first 5 weeks of life, but only those populations capable of culture were studied [9]. Infectious bacterial populations have been specifically interrogated via development of microbial species-specific diagnostic tools [10–12].…”

Section: Introductionmentioning

confidence: 99%

Utilizing the fecal microbiota to understand foal gut transitions from birth to weaning

et al. 2019

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A healthy gastrointestinal (GI) tract with a properly established microbiota is necessary for a foal to develop into a healthy weanling. A foal’s health can be critically impacted by aberrations in the microbiome such as with diarrhea which can cause great morbidity and mortality in foals. In this study, we hypothesized that gut establishment in the foal transitioning from a diet of milk to a diet of grain, forage, and pasture would be detectable through analyses of the fecal microbiotas. Fecal samples from 37 sets of foals and mares were collected at multiple time points ranging from birth to weaning. Bacterial DNA was isolated from the samples, and the V4 domain of bacterial 16S rRNA genes were amplified via polymerase chain reaction. Next generation sequencing was then performed on the resulting amplicons, and analyses were performed to characterize the microbiome as well as the relative abundance of microbiota present. We found that bacterial population compositions followed a pattern throughout the early life of the foal in an age-dependent manner. As foals transitioned from milk consumption to a forage and grain diet, there were recognizable changes in fecal microbial compositions from initial populations predominant in the ability to metabolize milk to populations capable of utilizing fibrous plant material. We were also able to recognize differences in microbial populations amongst diarrheic foals as well as microbial population differences associated with differences in management styles between facilities. Future efforts will gauge the effects of lesser abundant bacterial populations that could also be essential to GI health, as well as to determine how associations between microbial population profiles and animal management practices can be used to inform strategies for improving upon the health and growth of horses overall.

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Section: Introductionmentioning

confidence: 99%

Utilizing the fecal microbiota to understand foal gut transitions from birth to weaning

et al. 2019

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“…Worldwide, there are few reports indicating that healthy and sick equines carry Campylobacter spp. 5,8,[32][33][34] and the latest published data from Norway 35 described few cases but rather, sporadic isolation of Campylobacter from horses (with unknown health status). Of note, different examination methods can lead to varied analysis results.…”

Section: Resultsmentioning

confidence: 99%

“…(eg, Campylobacter jejuni – C. jejuni ) were predominantly detected in sick equines but rarely found in healthy horses. 5 , 6 However, there is growing evidence of their presence in healthy equines across the world. 7 , 8 …”

Section: Introductionmentioning

confidence: 99%

“…(eg, Campylobacter jejuni -C. jejuni) were predominantly detected in sick equines but rarely found in healthy horses. 5,6 However, there is growing evidence of their presence in healthy equines across the world. 7,8 According to the World Health Organization, Campylobacter is the most common bacterial pathogen causing human gastroenteritis.…”

Section: Introductionmentioning

confidence: 99%

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Molecular Identification of Infectious Enteropathogens in Faeces of Healthy Horses

Paruch

2022

Microbiol�Insights

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Zoogenic faecal contamination of the environment is one of the indices included in the evaluation of ecological threats, health hazards and adverse impacts on various ecosystems. The risks and environmental concerns are associated with the fact that faeces of wild and domesticated animals constitute the largest source of environmental loading of enteropathogens associated with transmission of zoonotic diseases (enteric zoonoses). Although sick animals are more likely to transmit pathogens, healthy ones can also be the carriers and defecate them into the environment. This is of particular importance given the close human-animal interactions and health effects resulting from human and ecological exposures to faecal hazards from companion and farm animals. We have therefore set out to investigate whether healthy equines can carry and defecate human infectious pathogens. For this purpose, we set up a pilot study to examine the faecal DNA of horses using culture-independent molecular diagnostics – fluorescent probe-based quantitative real-time PCR. Our results revealed that among a total of 23 horses, 6 were found to carry Campylobacter jejuni ( C. jejuni), and 5 had Salmonella enterica serovar Typhimurium ( S. Typhimurium). Moreover, Enterococcus faecalis ( E. faecalis) was found in 14 horses, while 19 were positive for Clostridium perfringens ( C. perfringens). Furthermore, the frequently reported protozoan parasites in livestock, Cryptosporidium parvum ( C. parvum) and Giardia lamblia ( G. lamblia), were discovered in 8 and 7 samples, respectively. This pilot study shed new light on the phenomenon of healthy horses carrying C. jejuni and other human-health-related enteropathogens.

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Diseases of the Alimentary Tract

2017

Veterinary Medicine

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Enteritis associated with infection by Campylobacter jejuni in two Thoroughbred foals

Cited by 4 publications

References 10 publications

Utilizing the fecal microbiota to understand foal gut transitions from birth to weaning

Utilizing the fecal microbiota to understand foal gut transitions from birth to weaning

Molecular Identification of Infectious Enteropathogens in Faeces of Healthy Horses

Diseases of the Alimentary Tract

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