We propose a new experiment to measure the running of the electromagnetic coupling constant in the spacelike region by scattering high-energy muons on atomic electrons of a low-Z target through the elastic process μ e → μ e. The differential cross section of this process, measured as a function of the squared momentum transfer t = q 2 < 0, provides direct sensitivity to the leading-order hadronic contribution to the muon anomaly a HLO μ . By using a muon beam of 150 GeV, with an average rate of ∼1.3 ×10 7 muon/s, currently available at the CERN North Area, a statistical uncertainty of ∼0.3% can be achieved on a HLO μ after two years of data taking. The direct measurement of a HLO μ via μe scattering will provide an independent determination, competitive with the time-like dispersive approach, and consolidate the theoretical prediction for the muon g-2 in the Standard Model. It will allow therefore a firmer interpretation of the measurements of the future muon g-2 experiments at Fermilab and J-PARC. a