Enrichment of vitamin E from Spirulina platensis microalga by SFE

Extraction and Characterization of Bioactive Compounds with Health Benefits from Marine Resources: Macro and Micro Algae, Cyanobacteria, and Invertebrates

“…Bioactive compounds from algal matter have been studied previously (vitamin E and carotenoids). For example, Mendiola et al ( 2008b ) optimized, by means of a central composite circumscribed design (CCCD), a process based on SFE at pilot scale, to obtain fractions highly enriched in vitamin E from Spirulina platensis (Mendiola et al 2008c ). The authors achieved a tocopherol enrichment of more than 12 times the initial concentration of tocopherol in the raw material by extracting with neat CO 2 at 361 bar and 83.3°C.…”

Supercritical Fluid Extraction of Bioactive Compounds: Fundamentals, Applications and Economic Perspectives

“…16). These compounds belong to the unsaponifiable fraction of plant oils and can be present together with other compounds like phospholipids, carotenoids, chlorophylls, and triterpenyl alcohols (Mendiola et al 2008). Studies have proven the importance of vitamin E in human health, due to its action as an antioxidant, in cancer prevention, etc.…”

Algae Extract Production Methods and Process Optimization

“…Supercritical extraction of algae was used for the investigation of vitamin E and carotenoids preparation. Mendiola et al optimized, on pilot scale, the preparation process of a fraction highly enriched in vitamin E from microalga S. platensis [22]. The process optimization at pressure 361 bar and temperature 83 ∘ C gave the authors over 12-fold increase of tocopherol content in relation to that in raw material.…”

“…Mendiola et al in their work used the RSM to optimize the process for obtaining the extract fractions highly enriched in vitamin E from S. platensis microalga [22]. The experiments were carried out according to the central composite circumscribed design (CCCD).…”