Enoxaparin Effect on Malondialdehyde Levels in Laparoscopic Cholecystectomy

Abstract

As a conclusion, mini dose of enoxaparin used sc'ly 2 hr before the operation, prevented the malondialdehyde increase during reperfusion period after laparoscopic cholecystectomy without causing any bleeding disorder while having no effect on serum alanine transferase, aspartate transferase increase.

The effects of enoxaparin on the liver in experimental pneumoperitoneum model

“…The highest tissue ALP levels were in the control group and although the levels in the enoxaparin group were lower than those of the control group, the difference was not statistically significant. The results obtained in the current study were similar to the results of our previous study 25 The conclusion of that study was that these elevated enzyme levels could be attributed in the main to the negative effects of the pneumoperitoneum on hepatic blood flow.…”

“…In a study by Lee et al 14 In a previous study by the current authors 25 , an evaluation was made of the effects of low dose enoxaparin on plasma MDA levels and liver function tests during laparoscopic cholecystectomy. At 20 mins after deflation, MDA levels were seen to have significantly increased in the control group compared with the enoxaparin group.…”