Enlargement of Sclerochoroidal Calcifications: Multimodal Imaging Update

Slean, Geraldine R.; Kalevar, Ananda; Chen, Judy; Johnson, Robert N.

doi:10.1097/icb.0000000000000644

Cited by 7 publications

(5 citation statements)

References 9 publications

(18 reference statements)

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“…Slean et al and Boutboul et al present two separate cases of SCC associated with such growth over more than 10 years, albeit without documented visual decline. 4,5 In the review by Shields et al and a previous case series by Hanovar et al with 38 eyes with SCC, the authors did not investigate whether SCC was associated with calcifications elsewhere in the orbit or globe. 1,2 In a study with 17 eyes with SCC, Fung et al 3 used enhanced depth imaging optical coherence tomography to demonstrate that all lesions included originated in the sclera with thinning or absence of the overlying choroid.…”

Section: Discussionmentioning

confidence: 99%

Sclerochoroidal Calcification With Optic Nerve Calcification in a Patient With Primary Hyperparathyroidism and Severe Vision Loss

Sood

Friedman

2024

RETINAL Cases &Amp; Brief Reports

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Background/Purpose: To present a case of sclerochoroidal calcification (SCC) associated with dural calcification along the optic nerves and severe visual loss.Methods: Case report.Results: A 74-year-old white female patient with a 25-year history of primary hyperparathyroidism and surgical removal of a single parathyroid gland presented with blurred vision. On presentation, she had a calcium level of 12.6 mg/dL (reference range: 8.7-10.3 mg/dL). Her best-corrected visual acuity (BCVA) was 20/40 in both eyes, and she was diagnosed with bilateral SCC. After 2 years, the patient returned with a complaint of progressive vision loss, and the BCVA was 20/150 in the right eye and hand motion in the left eye. She had stable focal SCC on fundus examination with no significant changes from the previous examination. The fluorescein angiogram was unremarkable with no leakage. Optical coherence tomography (OCT) of the macula showed no edema or subretinal fluid and was not significantly changed from the first OCT. B-scan showed areas of calcification in the sclera consistent with the SCC. Computerized tomography (CT) scans showed dural calcifications along both optic nerves. She had no enlargement of SCC lesions and no other ocular or neurologic pathology associated with her vision loss. Conclusion:We present a patient with bilateral SCC and associated calcification in both globes. Unlike previous reports of SCC, our case demonstrated progressive severe vision loss because of dural calcification along the optic nerves. Patients with SCC and decreased vision should receive a CT scan to look for this rare associated finding.

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Section: Discussionmentioning

confidence: 99%

Sclerochoroidal Calcification With Optic Nerve Calcification in a Patient With Primary Hyperparathyroidism and Severe Vision Loss

Sood

Friedman

2024

RETINAL Cases &Amp; Brief Reports

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“…Nevertheless, the lesion was found to be larger 10 years later. 48 CNV associated with SCC is the most common cause of vision loss in SCC. CNV is associated with subretinal fluid, subretinal hemorrhages, exudates, and hemorrhagic RPE detachments.…”

Section: Dovepressmentioning

confidence: 99%

Diagnosis and Management Strategies in Sclerochoroidal Calcification: A Systematic Review

Gündüz,

Tetik

2023

OPTH

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Sclerochoroidal calcification (SCC) is a rare disease which is characterized by calcium deposition in the sclera. The choroid is secondarily involved. Typical localization is in the midperipheral region, outside the vascular arcades. SCC is mostly located in the superotemporal quadrant. Often times, the patients are referred with the diagnosis of an amelanotic tumor. SCC may be dystrophic or metastatic. Metastatic SCC lesions are associated with conditions altering calcium and phosphate metabolism including primary and secondary hyperparathyroidism, vitamin D intoxication, renal failure, hyperphosphatemia, and destructive bony lesions. SCC lesions have a characteristic appearance and appear as distinct, ill-defined, yellow-white, elevated scleral/choroidal masses funduscopically. The purpose of this literature review is to review the current knowledge on SCC, highlight the imaging features, and discuss the differential diagnosis as well as management options.

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“…Lézie zostávajú stabilné a časom sa nezväčšujú [4]. Ale bol popísaný prípad idiopatických SCHK s objavením nových lézií a zväčšením existujúcich kalcifikácií v priebehu 10 rokov [10].…”

Section: Diskusiaunclassified

Idiopathic Sclerochoroidal Calcifications. A Case Report

Šulavíková¹,

Káčerik²,

Šustykevičová³

et al. 2022

CSO

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Aim: Sclerochoroidal calcifications (SCHC) are an uncommon benign ocular condition that occurs in elderly patients. SCHC usually manifest as multiple placoid yellow lesions in the midperipheral fundus, most often in the upper temporal quadrant. They are asymptomatic and often discovered during routine eye examinations in a patient with good visual acuity and visual field. According to the etiology, SCHC are divided into idiopathic, metastatic and dystrophic. Case reports: This is case report of 2 patients with idiopathic SCHC, who underwent basic eye examinations, fundus photography, optical coherence tomography, ultrasonography, fluorescein angiography, fundusautofluorescence, laboratory screening and in the second case also CT head scan. Conclusion: The aim of this publication is to point out the typical features of SCHC and their distinction from more serious conditions that they may resemble.

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Enlargement of Sclerochoroidal Calcifications: Multimodal Imaging Update

Abstract: The authors present a rare case of sclerochoroidal calcification enlargement over the course of 10 years using multimodal imaging.

Cited by 7 publications

References 9 publications

Sclerochoroidal Calcification With Optic Nerve Calcification in a Patient With Primary Hyperparathyroidism and Severe Vision Loss

Sclerochoroidal Calcification With Optic Nerve Calcification in a Patient With Primary Hyperparathyroidism and Severe Vision Loss

Diagnosis and Management Strategies in Sclerochoroidal Calcification: A Systematic Review

Idiopathic Sclerochoroidal Calcifications. A Case Report

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