Enlarged mediastinal lymph nodes in bronchogenic carcinoma: assessment with dynamic contrast-enhanced MR imaging. Work in progress.

Laissy, J P; Gay-Depassier, P; Soyer, Philippe; Dombret, Marie-Christine; Murciano, G; Sautet, Alain; Aubier, Michel; Menu, Y.

doi:10.1148/radiology.191.1.8134585

Cited by 45 publications

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“…Our results are in accordance with Laissy et al's study [30] of nine patients with bronchogenic carcinomas where a peak enhancement at 60±80 s after contrast injection was found in metastatic mediastinal lymph nodes, with a slow decrease until 6 min. In the same study [30] inflammatory enlarged mediastinal lymph nodes showed a more delayed increase in signal intensity and a lower peak signal intensity compared with metastatic lymph nodes. Gallardo et al [21] recently reported strong and rapid uptake of intravenous contrast in three cases of intramammary lymph nodes with lymphoid hyperplasia.…”

Section: Discussionsupporting

confidence: 93%

Axillary lymph node metastases in breast cancer: preoperative detection with dynamic contrast-enhanced MRI

et al. 2000

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Metastatic involvement of axillary lymph nodes is one of the most important prognostic variables in breast cancer. The aim of our work was to study the value of dynamic contrast-enhanced MR imaging in revealing axillary lymph node metastases from breast cancer. A total of 65 patients with invasive breast cancer treated with axillary lymph node dissection were preoperatively evaluated by MRI. T1-weighted dynamic contrast-enhanced 3D images were acquired using a coil covering the breast and the axilla. The dynamic contrast enhancement, size, and morphology of the axillary lymph nodes were registered. Histopathological examination revealed axillary lymph node metastases in 24 patients. When using a signal intensity increase in the lymph nodes of >100% during the first postcontrast image as a threshold for malignancy, 57 of 65 patients were correctly classified (sensitivity 83%, specificity 90%, accuracy 88%). These results were not improved when lymph node size and morphology were used as additional criteria. Axillary lymph nodes can be evaluated as a part of an MR-mammography study without substantial increase in examination time, and provide the surgeon with knowledge about the localization of possible metastatic lymph nodes.

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Section: Discussionsupporting

confidence: 93%

Axillary lymph node metastases in breast cancer: preoperative detection with dynamic contrast-enhanced MRI

et al. 2000

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“…In series comparing CT and MRI, the detection rate of nodal metastases was similar [41, 53, 59]. The hope of increasing sensitivity using dynamic enhanced MRI [60] and MR lymphography [7] has yet not been confirmed. Today, PET-CT is clearly the non-invasive method of choice for lymph node staging in lung cancer.…”

Section: Stagingmentioning

confidence: 99%

CT and MRI of Lung Cancer

Laurent

Montaudon²,

Corneloup³

2006

Respiration

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Computed tomography (CT) is still the cornerstone of imaging studies in the preoperative staging and post- therapeutic evaluation of lung cancer. The most recent developments in multidetector technology have dramatically improved the temporal and spatial resolution of CT. In the mean time, magnetic resonance imaging (MRI) has not become a routine examination in lung imaging and is today only used as a problem-solving tool in patients in whom CT remains equivocal. This article will describe the current tools developed in the multidetector CT era for evaluating the lung, and state-of-the-art MR examination of the chest. Then, the role of CT and MRI in nodule detection, the distinction between benign and malignant nodules, and the benefit of CT and MRI in the staging and post-therapeutic evaluation of lung cancer will be covered.

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“…Therefore, an enlarged node with calcification might be considered to be malignant on MRI but still diagnosed as benign on the basis of CT findings. Furthermore, small clustered LNs on MRI may mimic an enlarged LN due to poor spatial resolution [13,24,33]. However, MRI provides more different planes in longitudinal anatomic evaluation such as the subcarinal and aortopulmonary regions, which are difficult to assess in axial plane [13,21,24,34,35].…”

Section: N-statusmentioning

confidence: 99%

CT and MRI for staging of locally advanced non-small cell lung cancer

Chern

Chang

2003

Lung Cancer

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Enlarged mediastinal lymph nodes in bronchogenic carcinoma: assessment with dynamic contrast-enhanced MR imaging. Work in progress.

Abstract: Dynamic contrast-enhanced MR images may provide informative data about the nature of enlarged MLNs in the preoperative assessment of lung carcinoma. Further studies are needed to investigate its usefulness in clinical practice.

Cited by 45 publications

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Axillary lymph node metastases in breast cancer: preoperative detection with dynamic contrast-enhanced MRI

Axillary lymph node metastases in breast cancer: preoperative detection with dynamic contrast-enhanced MRI

CT and MRI of Lung Cancer

CT and MRI for staging of locally advanced non-small cell lung cancer

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