Enhancing targeted cancer therapy through multiple drug delivery by silk peptide nanoparticles
Zi‐Hao He,
Li‐Jin Qi,
Xiao‐Yan He
et al.
Abstract:Targeted therapy drugs exert an essential role in precision therapy in cancer treatments. However, their therapeutic efficiency is greatly limited by the poor water solubility and low bioavailability. Herein, by using an epidermal growth factor receptor (EGFR) targeted drug, erlotinib (ERL), as a representative of targeted therapy drugs, we demonstrate silk peptide (SP) extracted from silkworm cocoons can be used as a drug carrier to co‐load curcumin (CUR) and ERL to achieve dramatically improved antitumor the… Show more
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