Enhancing neovascularization post-myocardial infarction through injectable hydrogel functionalized with endothelial-derived EVs
Fabio Maiullari,
Marika Milan,
Maila Chirivì
et al.
Abstract:Over the past three decades, cell therapy development has fallen short of expectations, with many cellular sources demonstrating a "Janus effect" and raising safety concerns. Extracellular vesicles (EVs), supported by advanced technologies, present a promising avenue in regenerative medicine, offering benefits such as immune tolerance and avoidance of negative aspects associated with cell transplants. Our previous research showcased enhanced and organized subcutaneous vascularization using three-dimensional bi… Show more
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