Enhancing ‘meaningfulness’ of functional assessments: UK adaptation of the Amsterdam IADL questionnaire

Stringer, Gemma; Leroi, Iracema; Sikkes, Sietske A.M.; Montaldi, Daniela; Brown, Laura J. E.

doi:10.1017/s1041610219001881

Cited by 6 publications

(2 citation statements)

References 35 publications

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“…However, WA scoring is much simpler, and this score is already available in the online platform used for IADL assessments. The authors of the validation study of the UK version of A-IADL-Q also used the WA scoring method in part of their study, which was in high concordance with the IRT scoring [23]. Our study showed that both scoring methods could be used in clinical practice and research with similar sensitivity and specificity.…”

Section: Discussionsupporting

confidence: 63%

Assessment of the Instrumental Activities of Daily Living in Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease: Diagnostic Accuracy of the Serbian Version of the Amsterdam Iadl Questionnaire

et al. 2023

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To establish a diagnosis of dementia, it is necessary, in addition to cognitive impairment, to prove the existence of a disorder of instrumental activities of daily living (IADL). The Amsterdam IADL Questionnaire is a reliable instrument translated into different languages. This study aims to assess the diagnostic accuracy of the Serbian version of the Amsterdam IADL Questionnaire. The study included 75 patients with mild cognitive impairment (MCI) and dementia due to Alzheimer's disease. The questionnaire was scored using the weighted average (WA) and item response theory (IRT) scoring method. Diagnostic accuracy was examined using receiver–operating characteristic (ROC) curves. The area under the curves (AUC) was calculated with 95% confidence intervals (CI). The correlation between IRT and WA scores was strong and significant (r=-0.980, p<0.001). The AUC for the IRT scores of A-IADL-Q was 0.832 (95% CI: 0.729 to 0.909), while the AUC for the WA scores of A-IADL-Q was 0.848 (95% CI: 0.746 to 0.920). Both were significantly different from the AUC of 0.5 (p<0.001). There was no significant difference between the AUCs of IRT and WA scoring (z=1.157; p=0.247). Cutoffs and the highest combination of sensitivity and specificity for the IRT (sensitivity 0.767; specificity 0. 844) and WA (sensitivity 0.744; specificity 0. 844) scores of A-IADL-Q were calculated. We have shown that A-IADL-Q has moderate diagnostic accuracy in differentiating dementia and MCI. This instrument can be used in combination with cognitive measures to diagnose dementia in its early stages.

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Section: Discussionsupporting

confidence: 63%

Assessment of the Instrumental Activities of Daily Living in Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease: Diagnostic Accuracy of the Serbian Version of the Amsterdam Iadl Questionnaire

et al. 2023

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“…personal finances and using new personal technology) which may be indicators of impending dementia [33]. The Amsterdam IADL scale has undergone international validation studies [34,35].…”

Section: Neurodegeneration (N)mentioning

confidence: 99%

Blueprint for a Brain Health Clinic to Detect and Manage Early-Stage Cognitive Decline: A Consensus Exercise

Leroi¹,

Peel²,

Rebecca³

et al. 2020

J Neurodegener Disord

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Background: It is possible that about 30% of all dementia is preventable by addressing many of the modifiable health and lifestyle risks important for overall physical health. Currently, people in the pre-dementia or very early dementia stage who are referred to Memory Assessment Services (MAS) in the UK receive minimal, if any, support and/or intervention. They are typically referred back to primary care until the full syndrome of dementia emerges. This represents a lost opportunity to modify the trajectory of the condition, intervene with disease modifying therapies (DMTs) when available, and delay the onset of a full dementia syndrome. Objective:We aimed to develop a blueprint for a pragmatic 'Brain Health Clinic' (BHC) that can be implemented alongside, or in conjunction with, conventional MAS.Methods: Using modified consensus methods, an interdisciplinary task force of clinicians with experience in the diagnosis and care of people with cognitive impairment and dementia, met on several occasions to review existing evidence, share clinical experience, and propose a model for a pragmatic, 'real life' BHC, as an extension of, or embedded within, a current MAS. Results:The BHC is a systems-based, integrated care approach that uses existing resources, and can be developed by reconfiguring the way current MAS are provided. It can support people with early-stage cognitive impairment to remain well for longer, potentially changing outcomes. The practical, evidencebased and user-friendly blueprint is available as a free online tool (depicted in figures throughout this article). It sets out a vision for managing early-stage cognitive decline using a 'preempt-prevent' approach that maximizes brain health and quality of life for the person at risk and their families. It sets the stage for implementation of validated, clinically useful biomarker batteries and DMT to be introduced when available, fostering personalized cognitive healthcare. Conclusion:Adapting existing services to address neurodegenerative cognitive decline in the very earliest stages is a key intervention for secondary prevention of dementia.

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Importance of a functional measure in the evaluation of patients in a memory clinic: Validation of the Serbian version of the Amsterdam instrumental activities of daily living questionnaire

Milošević

Malobabić

Stojanović

et al. 2022

Clinical Neurology and Neurosurgery

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Enhancing ‘meaningfulness’ of functional assessments: UK adaptation of the Amsterdam IADL questionnaire

Cited by 6 publications

References 35 publications

Assessment of the Instrumental Activities of Daily Living in Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease: Diagnostic Accuracy of the Serbian Version of the Amsterdam Iadl Questionnaire

Assessment of the Instrumental Activities of Daily Living in Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease: Diagnostic Accuracy of the Serbian Version of the Amsterdam Iadl Questionnaire

Blueprint for a Brain Health Clinic to Detect and Manage Early-Stage Cognitive Decline: A Consensus Exercise

Importance of a functional measure in the evaluation of patients in a memory clinic: Validation of the Serbian version of the Amsterdam instrumental activities of daily living questionnaire

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