Enhancing lutein productivity of Chlamydomonas sp. via high-intensity light exposure with corresponding carotenogenic genes expression profiles

Ma, Ruijuan; Zhao, Xurui; Xie, Youping; Ho, Shih‐Hsin; Chen, Jianfeng

doi:10.1016/j.biortech.2018.12.109

Cited by 60 publications

(14 citation statements)

References 25 publications

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“…CTP4 for carotenoid biosynthesis and examined that lutein amount increased 1.5-fold under higher light intensities (170 and 280 µmol photons m −2 s −1 ), but in contrast to Zhao et al [48], found a temperature increase from 20 to 35 • C, after only two days at a light intensity of 170 µmol photons m −2 s −1 , yielded the highest lutein productivity (3.17 ± 0.18 mg g −1 dry weight biomass). Ma et al [50] also examined light stress on the marine microalga Chlamydomonas sp. JSC4 as a potential lutein production.…”

Section: Microalgae Cultivation For Commercial Lutein Production and mentioning

confidence: 99%

Marine Microalgae for Potential Lutein Production

2020

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Lutein is particularly known to help maintain normal visual function by absorbing and attenuating the blue light that strikes the retina in our eyes. The effect of overexposure to blue light on our eyes due to the excessive use of electronic devices is becoming an issue of modern society due to insufficient dietary lutein consumption through our normal diet. There has, therefore, been an increasing demand for lutein-containing dietary supplements and also in the food industry for lutein supplementation in bakery products, infant formulas, dairy products, carbonated drinks, energy drinks, and juice concentrates. Although synthetic carotenoid dominates the market, there is a need for environmentally sustainable carotenoids including lutein production pathways to match increasing consumer demand for natural alternatives. Currently, marigold flowers are the predominant natural source of lutein. Microalgae can be a competitive sustainable alternative, which have higher growth rates and do not require arable land and/or a growth season. Currently, there is no commercial production of lutein from microalgae, even though astaxanthin and β-carotene are commercially produced from specific microalgal strains. This review discusses the potential microalgae strains for commercial lutein production, appropriate cultivation strategies, and the challenges associated with realising a commercial market share.

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Section: Microalgae Cultivation For Commercial Lutein Production and mentioning

confidence: 99%

Marine Microalgae for Potential Lutein Production

2020

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“…[2] Furthermore, artificial light may trigger biomolecules production, as was recently reviewed. [3] In microalgal cultivation, moreover, inefficient light energy usage due to photoprotective mechanisms employed under highlight intensities may cause inefficient light energy usage. [4] In this work, we propose to employ flashing lights as a promising approach for optimizing the energy usage by matching the photosynthetic reaction kinetics in microalgae.…”

Section: Introductionmentioning

confidence: 99%

Combined effect of nutrient and flashing light frequency for a biochemical composition shift in Nannochloropsis gaditana grown in a quasi‐isoactinic reactor

et al. 2020

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Artificial lighting may be an interesting opportunity for the cultivation of microalgae as an alternative to natural sunlight. In particular, light emitting diodes (LEDs) can be employed to tailor the lighting to the microalgal culture in a controlled mode in order to create flashing light. In order to establish the effect of the flashing frequency on growth and biochemical composition of a model microalga, a quasi‐isoactinic reactor, in which the light distribution is almost homogeneous, was set up. In this work, it was employed for the cultivation of the heterokont Nannochloropsis gaditana in two growth media with limiting and nonlimiting nutrients. The combined effect of nutrient concentration and flashing frequency on the growth, lipid content, fatty acid content, and pigment content was assessed for the first time. The results indicate that both nutrient concentration and flashing frequency influence the above‐mentioned parameters. In particular, under flashing light conditions, an increase of lipid content and a decrease of polyunsaturated fatty acids (PUFAs) and chlorophyll are observed when nutrients are deficient, while the opposite effects are shown when nutrients are abundant.

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“…Light utilization is one of the important factors for algal growth and lutein production (Table S5). − Even though several earlier reports , predict the nutrient depletion-induced toxicity on algal cells at higher surface area and adsorption capacity, the CHNs’ interaction with algal cells exhibited a tremendous increase in growth activity and production of bioactive compounds. This phenomenon can be affirmed by the higher concentrations of Chl a (14.2 μg/mL) even during the poststationary growth phase of C.…”

Section: Resultsmentioning

confidence: 93%

Crystalline Domains Nested on Two-Dimensional Nanosheets as Heterogeneous Nanomachineries for the Sustainable Production of Bioactive Compounds from Chlorella sorokiniana

Agarwal

Jeevanandham

Kar

et al. 2022

ACS Sustainable Chem. Eng.

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Naturally occurring bioactive compounds have attracted significant interest from the perspective of scientific and industrial aspects owing to the wide range of technological, economic, and healthcare benefits. Their synthetic origin still suffers from several impeding challenges, such as expensive extraction and low yield. To address these critical issues, a unique hybridized system termed “algal-nanohybrids” was established by integrating green microalgae, Chlorella sorokiniana, with carbon-based heterostructured nanomaterials (CHNs), enhancing the microalgal growth for the sustainable augmentation of bioactive compounds as renewable sources of secondary metabolites. Hitherto, this work presents a new avenue in the formation of CHNs comprising propene-bridged cyanurate tetramer crystals nested on two-dimensional (2D) nanosheets, possessing excellent photocatalytic activity along with biocompatibility for the sustainable production of bioactive compounds. Mechanistic insights into the formation of CHNs and their plausible interaction with the algal cells were deciphered using a suite of characterization techniques. The conceptual significance of CHNs was elaborated, as an efficient nanomachinery for bolstering the enhanced production of lutein (97%) from C. sorokiniana, which is higher than that reported for other lutein-producing microalgae grown under photoautotrophic conditions. Interestingly, CHNs not only promoted microalgal biomass by 88% but also enhanced the production of chlorophyll a and carotenoids by 42 and 75%, respectively. This unprecedented work advances the synthesis of biocompatible CHNs, which can provide a breakthrough in the industry for the production of natural lutein and other bioactive compounds from microalgae.

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Enhancing lutein productivity of Chlamydomonas sp. via high-intensity light exposure with corresponding carotenogenic genes expression profiles

Cited by 60 publications

References 25 publications

Marine Microalgae for Potential Lutein Production

Marine Microalgae for Potential Lutein Production

Combined effect of nutrient and flashing light frequency for a biochemical composition shift in Nannochloropsis gaditana grown in a quasi‐isoactinic reactor

Crystalline Domains Nested on Two-Dimensional Nanosheets as Heterogeneous Nanomachineries for the Sustainable Production of Bioactive Compounds from Chlorella sorokiniana

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