Enhancing Loop-Mediated Isothermal Amplification through Nonpowered Nanoelectric Preconcentration
Na Eun Lee,
Kang Hyeon Kim,
Youngkyu Cho
et al.
Abstract:The global threat posed by the COVID-19 pandemic has catalyzed the development of point-of-care (POC) molecular diagnostics. While loop-mediated isothermal amplification (LAMP) stands out as a promising technique among FDAapproved methods, it is occasionally susceptible to a high risk of false positives due to nonspecific amplification of a primer dimer. In this work, we report an enhancing LAMP technique in terms of assay sensitivity and reliability through streamlined integration with a nonpowered nanoelectr… Show more
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