Enhancing Liver Delivery of Gold Nanoclusters via Human Serum Albumin Encapsulation for Autoimmune Hepatitis Alleviation
Cong Meng,
Yu Liu,
Yuping Ming
et al.
Abstract:Peptide-protected gold nanoclusters (AuNCs), possessing exceptional biocompatibility and remarkable physicochemical properties, have demonstrated intrinsic pharmaceutical activity in immunomodulation, making them a highly attractive frontier in the field of nanomedicine exploration. Autoimmune hepatitis (AIH) is a serious autoimmune liver disease caused by the disruption of immune balance, for which effective treatment options are still lacking. In this study, we initially identified glutathione (GSH)-protecte… Show more
The advancement of gold nanoclusters (Au NCs) gives rise to a new era in fabricating functional materials due to their controllable morphology, stable optical properties, and excellent biocompatibility. Based on...
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