Background: Children will be disproportionately impacted by climate change throughout their lives. Photovoice is a particularly useful tool for engaging and working with school-age children through sharing of students' personal knowledge and experiences visually and promotes meaningful dialogue on complex issues like climate change within classroom activities. Aim: The aim of the study is to evaluate the effect of climate change photovoice program on knowledge, attitude, and daily life practices among school-age children." Design: Quasiexperimental research design was used (pretest-posttest design). Settings: The study was conducted in Sayraa shared governmental preparatory school in Markaz Kafr El Dawwar educational directorate affiliated to El-Beheira Governorate. Subjects: By using a multistage sampling technique, preparatory school students in the first, second or third grades were selected. Tools: Four data collection tools were used to collect the data as follows: Tool I: Students' Sociodemographic Characteristics Structured Questionnaire Sheet, Tool II: Students' Knowledge Regarding Climate Change Structured Questionnaire Sheet, Tool III: Students' Attitudes towards Climate Change Structured Questionnaire Sheet, & Tool IV: Students' Reported Daily Life Practices for Climate Change Structured Questionnaire Sheet. Results: It was found that there is a statistically significant difference between pre, immediately post and after 3 months among the intervention group regarding knowledge, attitude and daily life practices regarding climate change after the implementation of the photovoice program. It was observed that there was a statistically significant relation between the level of knowledge, attitude and daily life practices among school-age children. There are many factors affecting the satisfactory level of knowledge, attitude and practices such as girl gender, high socioeconomic score and third preparatory level school-age children. Conclusion: it can be concluded that climate change photovoice program had a significant effect on school-age children's knowledge, attitude and daily life practices regarding climate change. Recommendations: The current study recommended applying a climate change photovoice program by school health nurses to improve awareness of school-age children. It also recommended promoting educational campaigns and intervention programs for various communities in Egypt by school health nurses targeting climate change.