Enhancing capacity for clinical practice guidelines in South Africa

Young, Taryn; Dizon, Janine Margarita; Kredo, Tamara; McCaul, Michael; Ochodo, Eleanor; Grimmer, Karen; Louw, Quinette

doi:10.11604/pamj.2020.36.18.20800

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…1 These guidelines are typically derived from evidence-based documents such as systematic reviews or meta-analyses, but can also arise from consensus meetings or other organizational practices. [2][3] Internationally, there is heterogeneity in the documentation, implementation, and use of clinical practice guidelines. For example, guidelines put forth by the World Health Organization (WHO) are intended for international use and are often adapted by clinicians in low-and-middle income countries to reflect resource availability and local practices.…”

Section: Introductionmentioning

confidence: 99%

Clinical guideline utilization in Uganda: A scoping review and comparison

et al. 2022

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Countries such as Uganda often depend on clinical practice guidelines from developed countries, non-profit charities, and international organizations. The sources and organizations that provide most of the guidelines used in Uganda are not well documented. The primary objective of this article was to determine whether a scoping review of scientific, peer-reviewed literature could identify the clinical guidelines actually used in Uganda. A secondary objective was to examine which organizations provided the majority of guidelines used. We therefore searched for consensus documents, guidelines, and meta-analyses published for use in African countries indexed in PubMed, OVID Medline, and Embase, and then surveyed guidelines currently in use in Ugandan medical practice. We thus compared these two sets of guidelines, as well as their breadth, geography, and sources, to make recommendations for similar low-income countries.

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Section: Introductionmentioning

confidence: 99%

Clinical guideline utilization in Uganda: A scoping review and comparison

et al. 2022

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Evaluating the impact of the global evidence, local adaptation (GELA) project for enhancing evidence-informed guideline recommendations for newborn and young child health in three African countries: a mixed-methods protocol

Kredo,

Effa,

Mbeye

et al. 2024

Health Res Policy Sys

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Background Poverty-related diseases (PRD) remain amongst the leading causes of death in children under-5 years in sub-Saharan Africa (SSA). Clinical practice guidelines (CPGs) based on the best available evidence are key to strengthening health systems and helping to enhance equitable health access for children under five. However, the CPG development process is complex and resource-intensive, with substantial scope for improving the process in SSA, which is the goal of the Global Evidence, Local Adaptation (GELA) project. The impact of research on PRD will be maximized through enhancing researchers and decision makers’ capacity to use global research to develop locally relevant CPGs in the field of newborn and child health. The project will be implemented in three SSA countries, Malawi, South Africa and Nigeria, over a 3-year period. This research protocol is for the monitoring and evaluation work package of the project. The aim of this work package is to monitor the various GELA project activities and evaluate the influence these may have on evidence-informed decision-making and guideline adaptation capacities and processes. The specific project activities we will monitor include (1) our ongoing engagement with local stakeholders, (2) their capacity needs and development, (3) their understanding and use of evidence from reviews of qualitative research and, (4) their overall views and experiences of the project. Methods We will use a longitudinal, mixed-methods study design, informed by an overarching project Theory of Change. A series of interconnected qualitative and quantitative data collections methods will be used, including knowledge translation tracking sheets and case studies, capacity assessment online surveys, user testing and in-depth interviews, and non-participant observations of project activities. Participants will comprise of project staff, members of the CPG panels and steering committees in Malawi, South Africa and Nigeria, as well as other local stakeholders in these three African countries. Discussion Ongoing monitoring and evaluation will help ensure the relationship between researchers and stakeholders is supported from the project start. This can facilitate achievement of common goals and enable researchers in South Africa, Malawi and Nigeria to make adjustments to project activities to maximize stakeholder engagement and research utilization. Ethical approval has been provided by South African Medical Research Council Human Research Ethics Committee (EC015-7/2022); The College of Medicine Research and Ethics Committee, Malawi (P.07/22/3687); National Health Research Ethics Committee of Nigeria (01/01/2007).

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Enhancing capacity for clinical practice guidelines in South Africa

Cited by 2 publications

References 31 publications

Clinical guideline utilization in Uganda: A scoping review and comparison

Clinical guideline utilization in Uganda: A scoping review and comparison

Evaluating the impact of the global evidence, local adaptation (GELA) project for enhancing evidence-informed guideline recommendations for newborn and young child health in three African countries: a mixed-methods protocol

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