Enhancement production of lipid and unsaturation of fatty acids in Cryptococcus humicola via addition of calcium ion

Machine learning encodes urine and serum metabolic patterns for autoimmune disease discrimination, classification and metabolic dysregulation analysis

“…[43][44][45][46][47][48][49][50][51] Perturbation of the biosynthesis of unsaturated fatty acids, fatty acid elongation, fatty acid degradation, fatty acid biosynthesis, glycerolipid metabolism, fatty acid elongation in mitochondria, fatty acid metabolism, steroid biosynthesis and bile acid biosynthesis were caused by the up-regulation of palmitic acid in disease groups, and the down-regulation of 3-oxodecanoic acid also affected fatty acid biosynthesis. [52][53][54][55][56][57][58][59] Other perturbed lipid-related metabolic pathways, including glycerophospholipid metabolism and the mitochondrial beta-oxidation of short-chain saturated fatty acids, were related to the down-regulation of phosphatidylcholine (PC) and octanoylcarnitine, respectively. 39,55 These regulations were critical for the homeostasis of cellular membranes and lipid stores.…”