Enhancement of yield and productivity in the 3-zone nonlinear SMB for succinic-acid separation under overloaded conditions

Choi, Jae Hwan; Nam, Hee Geun; Mun, Sungyong

doi:10.1016/j.jiec.2017.09.029

Cited by 3 publications

(1 citation statement)

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“…The SMB was constituted with a three‐zone open‐loop configuration and each zone was equipped with one column. More than 99% purity could be achieved under overloaded conditions after desorbent, extrication, feed loading and raffinate collection . Zeolites were found to have the ability to adsorb acids, such as succinic and acetic acids, selectively and efficiently.…”

Section: Downstream Processingmentioning

confidence: 99%

Bio‐based succinic acid: an overview of strain development, substrate utilization, and downstream purification

Dai

Guo

Zhang

et al. 2019

Biofuels Bioprod Bioref

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Succinic acid is an industrially important platform chemical that could be used as precursor for the establishment of a sustainable chemical industry. Due to the depletion of crude oil and the need for sustainable development, the biological production of succinic acid from renewable resources has attracted wide attention. To establish an economical bio‐based succinic acid production process, various metabolic engineering strategies have been developed and applied to improve the strain performance, including efficient CO2 fixation, by‐product elimination, use of metabolic modeling approaches, engineering of transcriptional regulations and optimization of reducing power balance. The utilization of renewable waste resources and the optimization of purification process have also been investigated to decrease the cost. This review will provide insights for current advances in succinic acid production and perspectives on further research to make bio‐based succinic acid production more efficient and economical. © 2019 Society of Chemical Industry and John Wiley & Sons, Ltd

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Section: Downstream Processingmentioning

confidence: 99%