Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein
Christopher L. D. McMillan,
Danushka K. Wijesundara,
Jovin J. Y. Choo
et al.
Abstract:The COVID-19 pandemic has highlighted the need for vaccines capable of providing rapid and robust protection. One way to improve vaccine efficacy is delivery via microarray patches, such as the Vaxxas high-density microarray patch (HD-MAP). We have previously demonstrated that delivery of a SARS-CoV-2 protein vaccine candidate, HexaPro, via the HD-MAP induces potent humoral immune responses. Here, we investigate the cellular responses induced by HexaPro HD-MAP vaccination. We found that delivery via the HD-MAP… Show more
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