Enhancement of antimicrobial and antimutagenic activities of Korean barberry (Berberis koreana Palib.) by the combined process of high‐pressure extraction with probiotic fermentation

Abstract

The combined HPE and fermentation process could be used as an alternative extraction method for improving the extraction efficacy of medicinal plants. The results will provide pharmaceutically useful information and potential direction for finding new drug sources from medicinal plants.

Enhancement of Bioactivity of Natural Extracts by Non-Thermal High Hydrostatic Pressure Extraction

“…In spite of this, the HHPE-fermented extracts of both the Korean barberry and the deodeok showed better antibacterial and mutagenic activities, in comparison to only HHPE and CE. Korean barberry showed significantly higher antibacterial activity against a β-lactam resistant Staphylococcus aureus and a β-lactam sensitive Staphylococcus aureus, as well as antimutagenic activity when compared to CE-NF and HHPE-NF [65]. Similarly, the fermented-HHPE extracts of deodeok exhibited the highest antimutagenic activities against TA 100, TA 1537 and TA 98 mutants of Salmonella typhimurium and a significant antibacterial activity against Listeria monocytogenes, S. aureus, Shigella boydii and S. typhimurium [66], possibly due to the production of specific secondary metabolites produced during the fermentation Table 5 The main individual flavonols identified in Opuntia cactus (Opuntia humifusa) extract using heat extraction, high hydrostatic pressure extractions (HHPE) at 100, 200 and 300 MPa, enzyme-assisted extraction (EAE), and the combination of HHPE and EAE (HHPE-EAE)…”

“…The potential application of the combined process of HHPE with probiotic fermentation was investigated as a technique for the enhancement of biological activities of Korean barberry (Berberis koreana) [65] and deodeok (Codonopsis lanceolata) extracts [66].…”

Enhancement of anti-inflammatory and antinociceptive actions of red ginseng extract by fermentation

“…These findings positively suggest that appropriate selection of useful bacteria could enhance desired efficacies of certain medicinal plants. In combination with high pressure extraction, probiotic fermentation has been suggested as an alternative method for improving the extraction efficiency and antimicrobial and antimutagenic activity of Korean barberry [8] …”

“…In combination with high pressure extraction, probiotic fermentation has been suggested as an alternative method for improving the extraction efficiency and antimicrobial and antimutagenic activity of Korean barberry. [8] In this communication, a water extract (RG) of red ginseng was subjected to fermentation with Bifidobacterium longum to produce its fermented water extract (FRG), and the pharmacological activity of RG and FRG were compared using experimental animal models.…”

Evaluation of Physicochemical Properties and Biological Activities of Steamed and Fermented Deodeok (Codonopsis lanceolata)

“…또한 발 효공정은 일반적으로 식품의 관능적 특성과 영양적 향상을 위해 전통 식품에 널리 사용되어 왔다 (13,14). 식물의 페놀 및 플라보 노이드의 함량은 발효과정을 통해 효과적으로 증가되어 항산화, 항미생물, 항암활성 등의 약리학적 특성을 향상시킨다 (15)(16)(17) α-Glucosidase 및 tyrosinase 효소활성 저해 증숙 및 발효 더덕추출물의 α-glucosidase 효소활성 저해에 대 NS-NF, non-steamed and non-fermented extract; NS-LF, non-steamed and L. rhamnosus fermented extract; S-NF, steamed and nonfermented extract; S-LF, steamed and L. rhamnosus fermented extract.…”