Enhancement effect of cell adhesion on titanium surface using phosphonated low-molecular-weight chitosan derivative

Kim, Eunhye; Park, Shin‐Hye; Chi, So-Yoon; Woo, Hee-Dong; Heo, Yun; Ito, Yoshihiro; Han, Dong Keun; Nah, Jae‐Woon; Son, Tae‐Il

doi:10.1007/s13233-015-3135-9

Cited by 8 publications

(2 citation statements)

References 31 publications

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“…Low molecular weight chitosan (LMC) has overcome these limits, and it is more readily to be absorbed by organism. Moreover, it has been proved that LMC possesses many outstanding health benefits such as anti-inflammatory, immunity regulation, antibacterial, antioxidant, and antilipid peroxidation 11 .…”

Section: Introductionmentioning

confidence: 99%

Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats

Zhang

Liu

et al. 2016

Acta Cir. Bras.

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PURPOSE:To evaluate the role of low molecular chitosan containing sepia ink (LMCS) in ethanol-induced (5 ml/kg) gastric ulcer in rats. METHODS:Animals were divided into four groups (n = 12): normal group (Normal), negative control group (Con), experiment group (LMCS) and positive control Omeprazole group (OMZ). Gastric empty rate was detected in the first 7 days. Rats were sacrificed at 7, 14 and 21 day for histology and ELISA detections. RESULTS:Gastric empty was no significant differences among the groups (P > 0.05). Histological observation showed gastric mucosal LMCS treated had better healing effect. Hydroxyproline (Hyp) was significantly increased from 7 day (P < 0.05). LMCS significantly inhibited malondialdehyde (MDA) generation for lipid peroxidation from 7 day (P < 0.05). LMCS significantly promoted the activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) at the earlier stage (P < 0.05). OMZ had the similar effects above. As for myeloperoxidase (MPO), LMCS significantly decreased and restored it to normal levels from 7 day (P < 0.05), it is earlier than OMZ which is from 14 day.CONCLUSION: LMCS can improve gastric mucosa tissue repair, exert significant influences on oxidative and antioxidant enzyme activities and neutrophil infiltration.

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Section: Introductionmentioning

confidence: 99%

Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats

Zhang

Liu

et al. 2016

Acta Cir. Bras.

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“…Nano-CS can also be used to coat the surface of oral implants to improve their surface properties and to enable the implant surfaces form ideal bone combinations with the surrounding alveolar bone [ 66 ]. Nano-CS does not exhibit cytotoxicity and is hydrophilic when it is used as a coating material, allowing proteins related to cell attachment, such as fibronectin, to attach and spread [ 66 , 67 ]. Meanwhile, nano-CS coating could inhibit the corrosion of Ni-Cr dental alloys, which is caused by S. mutans and may produce toxic products or affect patients who are susceptible to allergies [ 68 ].…”

Section: Application Of Nano-cs In Bone Tissue Engineeringmentioning

confidence: 99%

The Application of Chitosan Nanostructures in Stomatology

2021

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Chitosan (CS) is a natural polymer with a positive charge, a deacetylated derivative of chitin. Chitosan nanostructures (nano-CS) have received increasing interest due to their potential applications and remarkable properties. They offer advantages in stomatology due to their excellent biocompatibility, their antibacterial properties, and their biodegradability. Nano-CSs can be applied as drug carriers for soft tissue diseases, bone tissue engineering and dental hard tissue remineralization; furthermore, they have been used in endodontics due to their antibacterial properties; and, finally, nano-CS can improve the adhesion and mechanical properties of dental-restorative materials due to their physical blend and chemical combinations. In this review, recent developments in the application of nano-CS for stomatology are summarized, with an emphasis on nano-CS’s performance characteristics in different application fields. Moreover, the challenges posed by and the future trends in its application are assessed.

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