Enhanced susceptibility to Trichuris muris infection of B10Br mice treated with the probiotic Lactobacillus casei

Dea-Ayuela, María Auxiliadora; Rama-Iñiguez, Sara; Bolás‐Fernández, F.

doi:10.1016/j.intimp.2007.10.003

Cited by 46 publications

(44 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…68 On the other hand, Lactobacillus was reported to be dominant within the vaginal microbiome of nonpregnant Chinese women who had vulvovaginal yeast infection, 69 suggesting that its presence increased the risk of yeast infection. Furthermore, Lactobacillus casei increased the susceptibility of rodents to intestinal nematodes, 70 whereas Lactobacillus rhamnosus reduced the duration of nematode infection. 71 Our findings suggest that vaginal Lactobacillus may increase susceptibility to Ascaris or prolong duration of infection, an observation not previously reported.…”

Section: Discussionmentioning

confidence: 99%

Interactions Among Urogenital, Intestinal, Skin, and Oral Infections in Pregnant and Lactating Panamanian Ngäbe Women: A Neglected Public Health Challenge

Gonzalez‐Fernandez¹,

Koski²,

Sinisterra³

et al. 2015

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Abstract. Interrelationships among bacteria, protozoa, helminths, and ectoparasites were explored in a cross-sectional survey of 213 pregnant and 99 lactating indigenous women. Prevalences in pregnancy and lactation, respectively, were: vaginitis (89.2%; 46.8%), vaginal trichomoniasis (75.3%; 91.1%), bacterial vaginosis (BV; 60.6%; 63.3%), hookworm (56.6%; 47.8%), asymptomatic bacteriuria/urinary tract infection (AB/UTI; 56.2%; 36.2%), cervicitis (33.3%; 6.3%), vaginal yeast (24.9%; 11.4%), Ascaris (32.5%; 17.4%), vaginal diplococci (20.4%; 31.6%), caries (19.7%; 18.2%), scabies (17.4%; 8.1%), and Trichuris (12.5%; 8.7%). Multiple regressions revealed positive associations during pregnancy (trichomoniasis and AB/UTI; diplococci and Ascaris) and lactation (yeast and scabies). Negative associations were detected in pregnancy (BV and trichomoniasis; hookworm and diplococci) and lactation (BV and yeast). Vaginal Lactobacillus reduced odds of diplococci in pregnancy and lactation, but increased Ascaris eggs per gram (epg) and odds of trichomoniasis in pregnancy and yeast in lactation. These associations raised a concern that treatment of one condition may increase the risk of another.

show abstract

Section: Discussionmentioning

confidence: 99%

Interactions Among Urogenital, Intestinal, Skin, and Oral Infections in Pregnant and Lactating Panamanian Ngäbe Women: A Neglected Public Health Challenge

Gonzalez‐Fernandez¹,

Koski²,

Sinisterra³

et al. 2015

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…Reduction of worm burden was reported in mice infected with Trichinella spiralis 3,4,25 and Toxocara canis 2,7 . The failure of probiotics in affecting parasite load was reported in rats 12 and mice 33 infected with T. spiralis , and finally, an enhancement of mice susceptibility to Trichuris muris was attributed to Lactobacillus casei administration 11 .…”

Section: Discussionmentioning

confidence: 99%

EFFECT OF Bifidobacterium animalis ON MICE INFECTED WITH Strongyloides venezuelensis

Oliveira-Sequeira

David

Ribeiro

et al. 2014

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

The administration of viable Bifidobacterium animalis was tested to induce resistance against Strongyloides venezuelensis infection in mice. Effects on parasite burden, worm length, egg output, and intestinal mucosal histology were evaluated. The oral administration of B. animalis, strain 04450B, starting 14 days before the inoculation of nematode larvae significantly decreased the worm burden and egg output. In probiotic treated animals, the percent reduction of adult worms in the intestine was of 33% and the reduction of egg production was of 21%, compared with those of the control group. The duodenum villous height and villous/crypt ratio were significantly higher in probiotic-treated mice, indicating that this group could be experiencing less intestinal damage. The present findings revealed that the administration of B. animalis for the amelioration of host response to nematode infections is biologically plausible and could have some potential for impacting public health. Meanwhile, further study is needed to delineate the nature and identity of the factor(s) involved in these beneficial effects.

show abstract

“…A recent study demonstrated that T.muris infection altered the gut microbiota in mice, and inhibited subsequent rounds of infection [9]. Conversely, Lactobacillus facilitates H. polygyrus and T. muris infections in mice [10, 11]. These opposing findings illustrate the inconsistent nature of helminth-microbiome interactions within their shared hosts.…”

Section: Introductionmentioning

confidence: 99%

Host sex and genotype modify the gut microbiome response to helminth infection

Ling

Steinel

Weber

et al. 2019

Preprint

View full text Add to dashboard Cite

2 0 and D.I.B. (email: 9 1 helminth infection, such as the maternally transmitted bacterium Spiroplasma that protects 9 2 Drosophila neotestacea against nematode parasitism [7], or Bifdobacterium animalis that 9 3 protects mice against Strongyloides venezuelensis infection [8]. A recent study demonstrated that 9 4 T.muris infection altered the gut microbiota in mice, and inhibited subsequent rounds of infection 9 5 [9]. Conversely, Lactobacillus facilitates H. polygyrus and T. muris infections in mice [10, 11]. 6These opposing findings illustrate the inconsistent nature of helminth-microbiome interactions 9 7 within their shared hosts. What biological variables explain such heterogeneous results? If we 9 8can identify the causes of these variable helminth-microbe associations, then we may be better 9 9 able to treat dysbiosis and/or macroparasite infections [12][13][14].

show abstract

Enhanced susceptibility to Trichuris muris infection of B10Br mice treated with the probiotic Lactobacillus casei

Cited by 46 publications

References 40 publications

Interactions Among Urogenital, Intestinal, Skin, and Oral Infections in Pregnant and Lactating Panamanian Ngäbe Women: A Neglected Public Health Challenge

Interactions Among Urogenital, Intestinal, Skin, and Oral Infections in Pregnant and Lactating Panamanian Ngäbe Women: A Neglected Public Health Challenge

EFFECT OF Bifidobacterium animalis ON MICE INFECTED WITH Strongyloides venezuelensis

Host sex and genotype modify the gut microbiome response to helminth infection

Contact Info

Product

Resources

About