Enhanced Proliferation and Accelerated Adipogenic Differentiation of Mesenchymal Stem Cells via Fe3O4-Insulin Conjugates Stimulation
Abstract:The culture of human Umbilical Cord derived Mesenchymal Stem Cells (UC-MSCs), as well as the control of its differentiation toward different tissue lineages, is a very important part of regenerative medicine. In the present work, a systematic study of Fe 3 O 4 nanoparticles and its insulin conjugates for growth and differentiation of UC-MSCs were carried out for the first time. The cell viability assay was performed using a number of analytical methods including MTT assay and cumulative population doubling tim… Show more
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