Enhanced PEDOT adhesion on solid substrates with electrografted P(EDOT-NH
            <sub>2</sub>
            )

Ouyang, Liangqi; Wei, Bin; Kuo, Chung‐Hao; Pathak, Sheevangi; Farrell, Brendan P.; Martin, David C.

doi:10.1126/sciadv.1600448

Cited by 140 publications

(168 citation statements)

References 72 publications

(113 reference statements)

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“…As shown in Figure e,f, negligible variation of the impedance was observed for both NAF and PSS after stimulation with respect to the initial state, confirming comparable stability when the materials were subjected to three million pulses of electrical stimulation stress under similar experimental conditions. It should be noted that the mechanical adhesion of PEDOT films can be significantly improved through the roughening of the underlying metal surface or, more efficiently, through the formation of covalent chemical bonds between the conductive film and the underlying surface …”

Section: Resultsmentioning

confidence: 99%

Electrodeposited PEDOT:Nafion Composite for Neural Recording and Stimulation

Carli

Bianchi

Zucchini

et al. 2019

Adv Healthcare Materials

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Microelectrode arrays are used for recording and stimulation in neurosciences both in vitro and in vivo. The electrodeposition of conductive polymers, such as poly(3,4‐ethylene dioxythiophene) (PEDOT), is widely adopted to improve both the in vivo recording and the charge injection limit of metallic microelectrodes. The workhorse of conductive polymers in the neurosciences is PEDOT:PSS, where PSS represents polystyrene‐sulfonate. In this paper, the counterion is the fluorinated polymer Nafion, so the composite PEDOT:Nafion is deposited onto a flexible neural microelectrode array. PEDOT:Nafion coated electrodes exhibit comparable in vivo recording capability to the reference PEDOT:PSS, providing a large signal‐to‐noise ratio in a murine animal model. Importantly, PEDOT:Nafion exhibits a minimized polarization during electrical stimulation, thereby resulting in an improved charge injection limit equal to 4.4 mC cm−2, almost 80% larger than the 2.5 mC cm−2 that is observed for PEDOT:PSS.

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Section: Resultsmentioning

confidence: 99%

Electrodeposited PEDOT:Nafion Composite for Neural Recording and Stimulation

Carli

Bianchi

Zucchini

et al. 2019

Adv Healthcare Materials

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“…Future efforts toward device miniaturization will offer the opportunity to monitor the response of electrogenic tissues (e.g., brain and cardiac tissues) at the single‐cell level and to selectively record and manipulate them in a closed‐loop way . Different than electrode coatings, where the conjugated polymer is deposited on the surface of a metal electrode, in OECTs, the substrate options are virtually infinite. As such, the design of materials leading to specific substrate/conjugated polymer interactions might provide the mechanical stability needed for in vivo applications.…”

Section: The Future Of Organic Electrochemical Transistorsmentioning

confidence: 99%

Active Materials for Organic Electrochemical Transistors

2018

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The organic electrochemical transistor (OECT) is a device capable of simultaneously controlling the flow of electronic and ionic currents. This unique feature renders the OECT the perfect technology to interface man-made electronics, where signals are conveyed by electrons, with the world of the living, where information exchange relies on chemical signals. The function of the OECT is controlled by the properties of its core component, an organic conductor. Its chemical structure and interactions with electrolyte molecules at the nanoscale play a key role in regulating OECT operation and performance. Herein, the latest research progress in the design of active materials for OECTs is reviewed. Particular focus is given on the conducting polymers whose properties lead to advances in understanding the OECT working mechanism and improving the interface with biological systems for bioelectronics. The methods and device models that are developed to elucidate key relations between the structure of conducting polymer films and OECT function are discussed. Finally, the requirements of OECT design for in vivo applications are briefly outlined. The outcomes represent an important step toward the integration of organic electronic components with biological systems to record and modulate their functions.

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“…After 2 min of ultrasonication, PEDOT stayed stable on the ITO surface. The same process was followed by Ouyang et al [85] in 2017, by electrografting EDOT-NH 2 followed by an electropolymerization of the EDOT moieties. Such PEDOT coatings turned to be stable after 1 h of ultrasonication compared to pure PEDOT which delaminated on ITO after a few seconds.…”

Section: Enhancement Of Adhesion Properties Of Pedot:pssmentioning

confidence: 92%

Fabrication and Use of Organic Electrochemical Transistors for Sensing of Metabolites in Aqueous Media

et al. 2018

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Featured Application: Sensing organic molecules in water.Abstract: This review first recalls the basic functioning principles of organic electrochemical transistors (OECTs) then focuses on the transduction mechanisms applicable to OECTs. Materials constituting the active semiconducting part are reviewed, from the historical conducting polymers (polyaniline, polypyrrole) to the actual gold standard, poly-3,4-ethylenedioxythiophene: polystyrene sulfonic acid (PEDOT:PSS), as well as the methods used to fabricate these transistors. The review then focuses on applications of OECTs for the detection of small molecules and more particularly of metabolites, with a distinction between enzymatic and non-enzymatic transduction pathways. Finally, the few patents registered on the topic of OECT-based biosensors are reviewed, and new tracks of improvement are proposed. applied to biosensing quite early, associated with enzymes [4][5][6]. This is because, due to their functioning mechanism (already identified at the time), they brought into play the same charge carriers as most biological functions, i.e., electrons but also ions, and were therefore sensitive both to electron transfer to/from redox enzymes or ions (e.g., protons) produced from other types of enzymes. This is a characteristic which distinguished them from organic field-effect transistors (OFETs), which started to raise the attention of researchers exactly at the same period (precisely, 1983 for the first polyacetylene-based OFET [7]), and a few years later for applications to gas sensing (halogens, ammonia, oxygen [8-10] or even vapors of H 2 O, NO or H 2 O 2 [11][12][13][14]). However, OFETs never really produced any applicable results in the framework of biosensors in aqueous environment because of high operating voltages, of several tens of volts, which impede any measurements because of water electrolysis. Ion-sensitive organic field-effect transistors (ISOFETs), based on the same working principles of their inorganic counterparts (ISFETs) developed earlier [15,16], solved this problem of high operating potential, the electrolyte being not in direct contact with the semiconductor. However, these devices were confined mostly to protons detection [17][18][19] or, in any case, to charged species.As we show in this review, OECTs use both potentiometry and amperometry in their working principles. In that sense, OECTs are devices that represent a bridge between ISOFETs and classical amperometry, which certainly explains their success. This area of research is very active and several reviews have already been published on OECTs in general, for example by Kergoat et al. [1] or Rivnay et al. [3], or on OECTs applied to biology, for example by Liao and Yan [20], Liao et al. [21], Strakosas et al. [22] or . This present review, after going back to the basic functioning principles, along with details on transductions applicable to OECTs, reviews materials, fabrication techniques and then sensing applications. We focus on the detection of small molecules and more part...

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Enhanced PEDOT adhesion on solid substrates with electrografted P(EDOT-NH ₂ )

Abstract: Electrografted films of amine-functionalized thiophenes significantly improve coating adhesion and maintain charge transport.

Cited by 140 publications

References 72 publications

Electrodeposited PEDOT:Nafion Composite for Neural Recording and Stimulation

Electrodeposited PEDOT:Nafion Composite for Neural Recording and Stimulation

Active Materials for Organic Electrochemical Transistors

Fabrication and Use of Organic Electrochemical Transistors for Sensing of Metabolites in Aqueous Media

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Enhanced PEDOT adhesion on solid substrates with electrografted P(EDOT-NH 2 )

Abstract: Electrografted films of amine-functionalized thiophenes significantly improve coating adhesion and maintain charge transport.

Cited by 140 publications

References 72 publications

Electrodeposited PEDOT:Nafion Composite for Neural Recording and Stimulation

Electrodeposited PEDOT:Nafion Composite for Neural Recording and Stimulation

Active Materials for Organic Electrochemical Transistors

Fabrication and Use of Organic Electrochemical Transistors for Sensing of Metabolites in Aqueous Media

Contact Info

Product

Resources

About

Enhanced PEDOT adhesion on solid substrates with electrografted P(EDOT-NH ₂ )