Enhanced Pain Control after Reduction Mammaplasty with Combination Bupivacaine and Dexamethasone Regional Block: A Double-Blind Randomized Controlled Trial

Abstract

structures plus vascular marker immunoreactivity. VEGF level was significantly higher in day 3 wound homogenate of treatment vs controls. RNA sequencing of fibroblasts revealed divergent transcriptomes between treatment groups.CONCLUSION: b 3 AR agonist treatment increased wound closure rate while enhancing wound matrix architecture and vascularity. Effects can be attributed to direct action on specific fibroblast populations or via paracrine stimulation on these, or other cell populations. Further investigations will aid in discerning the potential use of this receptor as a therapeutic target in wound healing.