Enhanced Monofocal Versus Conventional Monofocal Intraocular Lens in Cataract Surgery: A Meta-analysis

Wan, Kelvin H; Au, Andrea C.K.; Kua, Wee Nie; Ng, Alex; Cheng, George P.M.; Lam, Nai Man; Chow, Vanissa W S

doi:10.3928/1081597x-20220707-01

Cited by 32 publications

(38 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of this optical bench study show that the new generation monofocal IOL, model ICB00, provided an extended range of focus and an improvement in simulated intermediate VA relative to standard aspheric monofocal IOL, while maintaining the same distance sVA. This is in agreement with the outcomes of the meta-analysis study of Wan et al [ 17 ] summarizing the results of 12 different clinical studies comparing ICB00 to standard monofocal IOLs that found that ICB00 provides an improvement in unaided intermediate vision with similar distance performance. Other clinical studies have shown a significant improvement in intermediate VA in patients implanted with the ICB00 IOL compared to the aspheric monofocal lens ZCB00 but no significant differences at distance [ 18 – 25 ].…”

Section: Discussionsupporting

confidence: 89%

Optical bench evaluation of the effect of pupil size in new generation monofocal intraocular lenses

et al. 2023

View full text Add to dashboard Cite

Background A new generation of enhanced monofocal IOLs has been introduced to slightly increase the depth of focus as compared to standard monofocal IOLs. The purpose of this study is to evaluate the effect of pupil size on the through-focus optical performance of three new enhanced monofocal IOLs, designed to improve the range of vision as compared to standard monofocal IOLs. Methods Optical bench testing in white light was performed for different pupils, using an average cornea eye. Distance image quality was evaluated using Modulation Transfer Function (MTF) measurements. Through-focus Visual Acuity (VA) was simulated from these measurements (sVA). Three enhanced monofocal IOLs (ICB00, ISOPure, and RayOne-EMV) and three standard monofocal IOLs: two aspheric (ZCB00 and SN60WF) and one spherical (AAB00) were included. Results The enhanced monofocal IOLs provided an improvement in the intermediate sVA as compared to standard monofocal IOLs. For ICB00, the improvement was independent of the pupil size, while for the ISOPure and RayOne-EMV, the intermediate sVA improved with increased pupil size. Similar to the spherical monofocal IOL, the ISOPure and RayOne-EMV showed a strong correlation between improvement in intermediate sVA and reduction of distance sVA and MTF, and increasing pupil size. ICB00 provided the same distance sVA as the aspheric monofocal IOLs and the lowest variability in MTF with pupil size. Conclusion Optical bench results showed that the ISOPure and RayOne-EMV provide similar performance to a spherical monofocal IOL, with a strong pupil dependency for distance and intermediate vision. The other enhanced monofocal IOL, ICB00, provided a sustained improvement in simulated intermediate VA and maintained distance image quality comparable to that of the standard aspheric monofocal IOLs, even for larger pupils.

show abstract

Section: Discussionsupporting

confidence: 89%

Optical bench evaluation of the effect of pupil size in new generation monofocal intraocular lenses

et al. 2023

View full text Add to dashboard Cite

show abstract

“…A preliminary search was conducted and two systematic reviews on the topic were identified [6,7]. The purpose these reviews was to assess the efficacy, spectacle independence, patient satisfaction, and adverse event rates in comparison with monofocal IOLs.…”

Section: Introductionmentioning

confidence: 99%

“…The purpose these reviews was to assess the efficacy, spectacle independence, patient satisfaction, and adverse event rates in comparison with monofocal IOLs. These systematic reviews concluded that new enhanced monofocal IOLs increased the intermediate and near vision in comparison to conventional monofocal IOLs, [6,7] without compromising the contrast sensitivity or inducing photic phenomena [6]. These reviews required a narrow scope including only an intervention IOL (Tecnis Eyhance) in comparison of other monofocal IOLs, [6] or even a particular monofocal model [7].…”

Section: Introductionmentioning

confidence: 99%

“…These systematic reviews concluded that new enhanced monofocal IOLs increased the intermediate and near vision in comparison to conventional monofocal IOLs, [6,7] without compromising the contrast sensitivity or inducing photic phenomena [6]. These reviews required a narrow scope including only an intervention IOL (Tecnis Eyhance) in comparison of other monofocal IOLs, [6] or even a particular monofocal model [7]. Conversely, this is the first scoping review covering a wide scope that explores not only the clinical results of enhanced monofocal IOLs in comparison to standard monofocal IOLs, but also in comparison to EDoF lenses and laboratory studies.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Positioning of enhanced monofocal intraocular lenses between conventional monofocal and extended depth of focus lenses: a scoping review

et al. 2023

View full text Add to dashboard Cite

Background New intraocular lenses (IOLs) have emerged since the originally coined monofocal and multifocal IOLs. The extended depth of focus (EDoF) and enhanced monofocal IOLs (mono-EDoF) that have appeared in the last decade have caused some confusion in their classification. The aim of this review was to summarize the outcomes provided by mono-EDOF IOLs and to determine which of the endpoints, described by the American National Standard (ANSI) for EDoF IOLs, are fulfilled. Methods The MEDLINE, EMBASE, and WEB OF SCIENCE databases were searched. Two independent reviewers screened the studies for inclusion and data extraction. The search strategy was limited to studies published between 2020 and 2022, but not by language. The results are presented as a narrative summary accompanied by tables, in alignment with the objectives of this scoping review. Compliance with the endpoints for clinical outcomes described in the American National Standard Z80.35–2018 (ANSI) for EDoF lenses was checked and additional endpoints were defined. Results Two systematic reviews, 13 laboratory, 21 clinical, and two mixed studies were included. Tecnis Eyhance was the mono-EDOF with the highest volume of evidence to date. Although laboratory studies included other IOLs, clinical evidence for them is still scarce, with only one study of IsoPure compared to a standard monofocal IOL. Evidence in comparison to EDoF lenses is also scarce, even for Tecnis Eyhance, with only three studies including this lens in comparison to an EDoF lens. After evaluation of the ANSI criteria, agreement was found in the failure for the increase in depth of field equal to or greater than 0.5 D for a visual acuity (VA) level of 0.2 logMAR and none of the studies supported that the median monocular VA at intermediate distance was at least 0.2 logMAR. Conclusions Additional clinical evidence is required for other mono-EDOF IOLs beyond Tecnis Eyhance. Until the arrival of a standard classification, mono-EDOF should be better still classified as monofocal because the ANSI standards were not fully met.

show abstract

“…However, a recent meta-analysis on enhanced monofocal IOLs has reported no increased risk of contrast sensitivity loss or increased incidence of photic phenomena [32].…”

Section: Declarations Fundingmentioning

confidence: 99%

Visual Outcomes and Patient Satisfaction after Bilateral Implantation of an Enhanced Monofocal Intraocular Lens: A Single Blind Prospective Randomized Study

Giglio

Vinciguerra

Presotto

et al. 2023

Preprint

View full text Add to dashboard Cite

Purpose: To evaluate and compare the visual outcomes of an enhanced monofocal IOL with two different monofocal IOLs. Setting: Eye Clinic, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy. Design: Prospective, single-centre, single-blind, randomized controlled clinical study. Methods: The study included patients undergoing phacoemulsification and IOL implantation. Patients were consecutively randomized by block randomization and assigned in a 1:1:1 allocation ratio to three study arms to bilaterally receive Tecnis® Eyhance (model ICB00) or Tecnis®1-piece (model ZCB00) or Alcon®1-piece (model Clareon, CNA0T0) respectively. Monocular and binocular (both corrected and uncorrected) visual acuities for far, intermediate and near were registered and compared among groups. To track changes in patient quality of life, the Catquest-9SF questionnaire was administered to each patient before and after cataract extraction. Results: A total of 90 patients (30 for each group) were enrolled. At 3 months follow-up, statistically significant differences for intermediate and near distance visual acuities were found between the three groups. Non-statistically significant differences were observed for distance visual acuities and the changes in Catquest-9SF scores. Conclusion: Tecnis® Eyhance ICB00 IOL provided better results in intermediate visual outcomes without negative effects on patients’ quality of life.

show abstract

Enhanced Monofocal Versus Conventional Monofocal Intraocular Lens in Cataract Surgery: A Meta-analysis

Cited by 32 publications

References 33 publications

Optical bench evaluation of the effect of pupil size in new generation monofocal intraocular lenses

Optical bench evaluation of the effect of pupil size in new generation monofocal intraocular lenses

Positioning of enhanced monofocal intraocular lenses between conventional monofocal and extended depth of focus lenses: a scoping review

Visual Outcomes and Patient Satisfaction after Bilateral Implantation of an Enhanced Monofocal Intraocular Lens: A Single Blind Prospective Randomized Study

Contact Info

Product

Resources

About