“…MiR-29b-3p is computationally predicted by miRanda to target the following tumour suppressor genes (TSGs): ADAMTS9, ARRDC3, CASP7, FEM1B, HBP1, HPGD, ING3, NAV3, PTEN, RhoBTBl, SEL1L, SLC5A8, SUV420H2, TET1, TET2 and UVRAG (24). Direct interactions between miR-29b-3p and the 3’-UTRs of colorectal cancer-suppressing TET1 and TET2 have been demonstrated by luciferase assays already (28), (29), (30). Interestingly, a different ITC, phenethyl isothiocyanate, was reported to inhibit the upregulation of miR-29b-3p in mouse lung tissue mediated by environmental cigarette smoke (31).…”