Enhanced Luminol Chemiluminescence with Oxidase-like Properties of FeOOH Nanorods for the Sensitive Detection of Uric Acid

Abstract

FeOOH nanorods, as one-dimensional nanomaterials, have been widely used in many fields due to their stable properties, low cost, and easy synthesis, but their application in the field of chemiluminescence (CL) is rarely reported. In this work, FeOOH nanorods were synthesized by a simple and environmentally friendly one-pot hydrothermal method and used for the first time as a catalyst for generating strong CL with luminol without additional oxidant. Remarkably, luminol-FeOOH exhibits about 250 times stronger CL than the luminol-H 2 O 2 system. Its CL intensity was significantly quenched by uric acid. We established a simple, rapid, sensitive, and selective CL method for the detection of uric acid with a linear range of 20−1000 nM and a detection limit of 6.3 nM (S/N = 3). In addition, we successfully applied this method to the detection of uric acid in human serum, and the standard recoveries were 95.6−106.4%.

Remarkably Enhanced Luminol/H2O2 Chemiluminescence with Excellent Peroxidase-like Activity of FeCoNi-based Metal-Organic Xerogels for the Sensitive Detection of Dopamine

“…Chemiluminescence (CL) is the phenomenon of luminescence resulting from chemical reactions of substances. , It has been widely used in many fields, such as drug analysis, clinical medicine, food testing, and environmental monitoring, owing to its features of high sensitivity, low background signal, fast analysis speed, simple instrumentation, etc. − Due to its advantages of easy availability, high stability, good water solubility, and high luminescence efficiency, luminol is by far one of the most widely used CL luminophores . Nevertheless, the conventional luminol/H 2 O 2 CL system suffers from low efficiency in converting chemical energy into light energy, thus greatly limiting its further development for analytical applications. − Accordingly, there is still a significant requirement for the establishment of innovative, high-performance CL systems and the development of efficient CL catalysts.…”

Engineering Molecular Emission Centers of Carbon Dots to Boost the Electrochemiluminescence for the Detection of Cancer Cells

“…This phenomenon provided strong evidence for molecular emission-dominated ECL of Lu-CDs. , In addition, as shown in the inset of Figure C, the synthetic Lu-CD solution was brown under natural light but intuitively exhibited light blue with the radiation of UV lamp (λ = 365 nm). Moreover, as shown in Figure D, the UV–vis adsorption wavelength of Lu-CDs was at 220 nm, probably originating from the π–π* transition of the graphitic carbon cores, while the characteristic peak at 350 nm was corresponding to the hydrazide groups in the Lu-CDs . These results provided important insights for molecular emission-dominated ECL of Lu-CDs.…”

Enhanced peroxidase-like activity of MOF nanozymes by co-catalysis for colorimetric detection of cholesterol

“…5B), accompanied by a detection limit of 1.1 μM ( S / N = 3). 39 In conclusion, the MoCu-2MI nanozyme successfully achieved the colorimetric detection of H 2 O 2 under near-neutral conditions, which was beneficial to the subsequent one-step detection of cholesterol. Then, the stability of the colorimetric detection of H 2 O 2 was explored.…”