Colonoscopy is an important diagnostic and screening tool for colorectal
cancer detection and prevention, and adequate bowel preparation is critical for
successful colonoscopy. Complications related to colonoscopy are increased in
elderly patients, either directly or indirectly related to the procedure, and
the risks and benefits of colonoscopy procedures need to be carefully considered
in these patients. Recent studies have shown that the 4 liter polyethylene
glycol with a split preparation is safe and effective for elderly patients, and
is the preferred preparation for patients with medical comorbidites.
Preparations containing sodium phosphate are generally not recommended for the
elderly due to increased renal complications. In addition, a low residue diet
may aid in tolerance and willingness to undergo the procedure compared with a
clear liquid diet, with comparable bowel preparation adequacy. Risk factors for
inadequate bowel preparations include poor adherence to split preparation
instructions or volume of solution ingested, and certain patient related
medications and comorbidities, such as diabetes, elevated body mass index, and
antidepressant or narcotic use. Methods for achieving safe and adequate bowel
preparations in the elderly include clear instructions, reminder calls, and case
management for potential confounding patient related factors.