Enhanced extraction of phenolic compounds from mango by-products using deep eutectic solvents

Ojeda, Gonzalo Adrián; Vallejos, Margarita; Sgroppo, Sonia Cecilia; Sánchez‐Moreno, Concepción; Ancos, Begoña de

doi:10.1016/j.heliyon.2023.e16912

Cited by 16 publications

(10 citation statements)

References 37 publications

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“…This selectivity of the DESs can be explained by different chemical interactions with the target compounds [ 165 ]. Ojeda et al [ 171 ] used mango by-product to extract bioactive compounds using DESs. To understand the relation between viscosity and the hydrogen bonds in the DESs, the authors performed a theoretical study and found out that the hydrogen bonds have a determining effect on the viscosity of the viscosity of the DES and in the specificity of the compounds extracted.…”

Section: Deep Eutectic Solvents For the Extraction Of Bioactive Compo...mentioning

confidence: 99%

A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest

Ferreira,

Sarraguça

2024

Pharmaceuticals

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The extraction of bioactive compounds of pharmaceutical interest from natural sources has been significantly explored in recent decades. However, the extraction techniques used were not very efficient in terms of time and energy consumption; additionally, the solvents used for the extraction were harmful for the environment. To improve the environmental impact of the extractions and at the same time increase the extraction yields, several new extraction techniques were developed. Among the most used ones are ultrasound-assisted extraction and microwave-assisted extraction. These extraction techniques increased the yield and selectivity of the extraction in a smaller amount of time with a decrease in energy consumption. Nevertheless, a high volume of organic solvents was still used for the extraction, causing a subsequent environmental problem. Neoteric solvents appeared as green alternatives to organic solvents. Among the neoteric solvents, deep eutectic solvents were evidenced to be one of the best alternatives to organic solvents due to their intrinsic characteristics. These solvents are considered green solvents because they are made up of natural compounds such as sugars, amino acids, and carboxylic acids having low toxicity and high degradability. In addition, they are simple to prepare, with an atomic economy of 100%, with attractive physicochemical properties. Furthermore, the huge number of compounds that can be used to synthesize these solvents make them very useful in the extraction of bioactive compounds since they can be tailored to be selective towards a specific component or class of components. The main aim of this paper is to give a comprehensive review which describes the main properties, characteristics, and production methods of deep eutectic solvents as well as its application to extract from natural sources bioactive compounds with pharmaceutical interest. Additionally, an overview of the more recent and sustainable extraction techniques is also given.

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Section: Deep Eutectic Solvents For the Extraction Of Bioactive Compo...mentioning

confidence: 99%

A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest

Ferreira,

Sarraguça

2024

Pharmaceuticals

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“…, phenolic compounds, carotenoids) from various plant materials, e.g. , pumpkin, 33 ginseng, 48 wine lees, 49 mango peels, 50 apple pomace, 51 mangoes, 52 Cosmos sulphureus , 53 orange peels, 54 Cinnamomum cassia bark 55 and blueberry leaves, 56 whereas the number of studies that use UAE coupled to DESs for such purposes has been steadily increasing. An overview of representative studies is presented in Table 1.…”

Section: Innovative Extraction Techniques Coupled To Dessmentioning

confidence: 99%

Coupling deep eutectic solvents with innovative extraction techniques towards plant derived bioactive compositions

Kyriakoudi,

Radojčić Redovniković,

Vidović

et al. 2024

RSC Sustain.

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“…Extractions were performed with ultrasound according to Ojeda et al (2023) with some modifications. Two solvents were used: 70% methanol (EUMe) and water (EUW).…”

Section: Ultrasound-assisted Solvent Extractionmentioning

confidence: 99%

“…These studies have demonstrated the capacity of these solvents to efficiently extract bioactive compounds, such as flavonoids, phenolic acids, anthocyanins, and alkaloids, from various plant-derived materials, mainly from residues of the agrifood industry, such as peels, hulls, seeds, pomace, and leaves. The extraction ability of this solvent has been investigated, among others, in date seed (Airouyuwa et al, 2023), olive leave (Alrugaibah et al, 2023), cocoa bean shell (Rebollo-Hernanz et al, 2021;Benítez-Correa et al, 2023), pomegranate peels, almond hulls, and elderberry pomace (Bertolo et al, 2023), buckthorn leaves (Cui et al, 2018), hazelnut skin (Mazzeo et al, 2023), mango by-products (Pal and Jadeja, 2020;Ojeda et al, 2023), sour cherry pomace (Popovic et al, 2022) and avocado peels (Posta et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

Extraction of phenolic compounds from lucuma (Pouteria lucuma) seeds with natural deep eutectic solvents: modelling using response surface methodology and artificial neural networks

Puma-Isuiza,

García-Chacón,

Osorio

et al. 2024

Front. Sustain. Food Syst.

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The present study aimed to extract polyphenolic compounds from lucuma (Pouteria lucuma) seeds using natural deep eutectic solvents (NADES) as a green, efficient, and environmentally friendly extraction. This was optimized by using the Response Surface Method (RSM) and comparing its predictive capacity with Artificial Neural Networks (ANN) and Convolutional Neural Networks (CNN). Four NADES were prepared by mixing lactic acid (LA) with each of the following reagents: sodium acetate (SA), urea (U), glucose (G), and ammonium acetate (AA), separately. The yield of total phenolic compounds (TPC) obtained from lucuma seeds with each NADES was measured as an optimization criterion with the Box-Benhken design. The following factors were evaluated: time, temperature, and the lucuma seed flour (LSF): NADES ratio. The response variables were TPC and antioxidant activity. The LA-AA extract was selected because it exhibited the highest TPC value and was analyzed by UHPLC–MS (Ultra-performance Liquid Chromatography-Mass Spectrometry). From the RSM, the optimal extraction parameters were 80 min, 52°C, and LSF: NADES ratio of 8:100 (w/v), obtaining a TPC value of 3601.51 ± 0.51 mg GAE/100 g LFS. UHPLC–MS analysis evidenced the formation of epigallocatechin isomers from epigallocatechin gallate. The predictive ability of ANNs compared to RSM was demonstrated.

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Enhanced extraction of phenolic compounds from mango by-products using deep eutectic solvents

Cited by 16 publications

References 37 publications

A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest

A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest

Coupling deep eutectic solvents with innovative extraction techniques towards plant derived bioactive compositions

Extraction of phenolic compounds from lucuma (Pouteria lucuma) seeds with natural deep eutectic solvents: modelling using response surface methodology and artificial neural networks

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