Enhanced Depth Imaging Optical Coherence Tomography of Small Choroidal Melanoma

Abstract

Small choroidal melanoma tumor thickness was overestimated by 55% on ultrasonography compared with EDI-OCT. The EDI-OCT features of small choroidal melanoma compared with choroidal nevus include increased tumor thickness, subretinal fluid, subretinal lipofuscin deposition, and retinal irregularities, including shaggy photoreceptors.

Clinical and Spectral-Domain Optical Coherence Tomography Appearance of Optic Disc Melanocytoma: A New Classification and Differentiation from Pigmented Choroidal Lesions

“…The density of posterior optical shadowing in choroidal melanoma and nevus is less prominent than in optic disc melanocytoma. While the majority of cases in both conditions demonstrate partial optical shadowing (73% in melanoma, 59% in nevus) [2], in optic disc melanocytoma, optical shadowing of heavily pigmented Type 1 lesions in present and previous studies is extremely dense.…”

“…The SD-OCT features of choroidal melanoma and nevus have been well described [1,2,3,4]. While a number of case reports and small case series include limited descriptions of the corresponding features of the classic, darkly pigmented optic disc melanocytoma, these have not included the uncommon, more lightly pigmented form of the tumor [5,6,7,8,9,10,11,12,13,14,15,16,17,18,19].…”

The highlights from experiences on Enhanced Depth Imaging-Optical Coherence Tomography

“…lipofuscin deposition, disruption in the external limiting membrane and the ellipsoid zone, irregularity in the layers including the inner plexiform and the ganglion cell. Additionally, in choroidal metastatic tumors, the differential findings from other pathologies in EDI-OCT are a plateau-shaped tumor with low internal reflectivity, ''shaggy photoreceptors'', and subretinal fluid with high-reflective speckles [61][62][63][64][65]. …”

Análise de sinais de tomografia por coerência óptica: equação LIDAR e métodos de inversão

“…Atualmente a técnica OCT vem sendo empregada, com maior ou menor grau de maturidade, em diversasáreas da saúde além da oftalmologia, como: dermatologia [41,42], oncologia [44,45], cardiologia [43,47] e odontologia [37,39], por exemplo. Além disso, aplicações não biologicas vem sendo demonstradas devido as vantagem apresentadas [55].…”

“…A medida das propriedadesópticas de tecidos biológicos de forma não invasiva são necessárias para diagnósticos médicos, como a distinção entre um tecido normal e alterado na pele [42,45]. A vantagem desta medida utilizando a técnica OCTé que esta pode ser feita de forma não invasiva e in vivo com alta resolução lateral e em profundidade.…”