Enhanced delivery of retinoic acid to breast cancer cells by folate receptor- targeted folic acid-conjugated glutenin nanoparticles for promising treatment of breast cancer
Raja Rajeswari Rajeshkumar,
Parasuraman Pavadai,
Theivendren Panneerselvam
et al.
Abstract:Targeted delivery via surface receptors can significantly improve the therapeutic efficacy and reduce the adverse drug reactions. The protein nanocarrier system offers many advantages, such as encapsulation in various drugs and molecules and prolonged circulation. Here, the folate receptor-targeted folic acid-conjugated retinoic acid-loaded glutenin nanoparticles (FA-RA-Glu NPs) were successfully synthesised for enhanced delivery of retinoic acid to breast cancer cells (MCF-7). After a complete physico-chemica… Show more
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