Enhanced Cellular Delivery of Tildipirosin by Xanthan Gum–Gelatin Composite Nanogels
Xianqiang Li,
Jinhuan Liu,
Jinfeng Dou
et al.
Abstract:Tildipirosin has no significant inhibitory effect on intracellular bacteria because of its poor membrane permeability. To this end, tildipirosin-loaded xanthan gum− gelatin composite nanogels were innovatively prepared to improve the cellular uptake efficiency. The formation of the nanogels via interactions between the positively charged gelatin and the negatively charged xanthan gum was confirmed by powder X-ray diffraction and Fourier transform infrared. The results indicate that the optimal tildipirosin com… Show more
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