Enhanced Bidirectional Gamma-band Granger Prediction in Fast Compared to Slow Performers in a 3-stimulus Oddball Task

Abstract

We used Granger prediction (GP) to assay fatigue effects in a 3-stimulus oddball task requiring context-sensitive proactive control to evaluate top-down frontal-parietal and bottom-up parietal-frontal gamma-band connectivity across two time windows - an earlier window associated with sensory processing and a later window associated with high level cognition. Results indicated frontal-parietal GP enhancement in better performers, though more so in the early versus later window. No differences emerged in parietal-frontal connectivity. Findings suggest observed differences are driven largely by early top-down frontal-parietal network activity. The observed pattern corresponds to connectivity in previous work, suggesting gamma-band GP could be a generalized indicator of central control and related motivational factors.